Authors: Eric J. Kremer1,∗ Main Text Most of us might be surprised by the rudimentary scientific rationale prevalent in the field of vaccine research just 50 years ago. For over […]
What are Adenovirus-Based Vaccines?
Authors: By Dr. Sanchari Sinha Dutta, Ph.D.Reviewed by Sophia Coveney, B.Sc. Adenoviruses are considered excellent vectors for delivering target antigens to mammalian hosts because of their capability to induce both innate and adaptive immune […]
Adenovirus-vectored Vaccines for COVID-19 – How Do They Work?
Authors: Heather D. Marshall, PhD | Vito Iacoviello, MD Viruses are genetic material surrounded by a protein shell with the ability to infect cells, highjack cellular machinery, and make copies of themselves. […]
Severe covid-19 pneumonia: pathogenesis and clinical management
Authors: Amy H Attaway, assistant professor of medicine, associate director, COPD center1, Rachel G Scheraga, assistant professor of medicine1 2, Adarsh Bhimraj, head, section of neurological infections; staff, infectious diseases1, Michelle […]
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection in Children and Adolescents A Systematic Review
Authors: Riccardo Castagnoli, MD1,2; Martina Votto, MD1,2; Amelia Licari, MD1,2; et al Key Points Question What are the clinical features of pediatric patients with coronavirus disease 2019 (COVID-19)? Findings In this systematic review of 18 studies with 1065 participants, most pediatric […]
COVID-19: Current understanding of its Pathophysiology, Clinical presentation and Treatment
Authors: Anant Parasher Abstract Background The severe acute respiratory syndrome (SARS) coronavirus-2 is a novel coronavirus belonging to the family Coronaviridae and is now known to be responsible for the outbreak […]
The role of extracorporeal membrane oxygenation in critically ill patients with COVID-19: a narrative review
Authors: Shiqian Huang, Shuai Zhao, Huilin Luo, Zhouyang Wu, Jing Wu, Haifa Xia & Xiangdong Chen BMC Pulmonary Medicine volume 21, Article number: 116 (2021) Abstract Extracorporeal life support treatments such as extracorporeal membrane oxygenation (ECMO) have been recommended for the treatment of […]
COVID-19 pathophysiology: A review
Authors: COVID-19 pathophysiology: A review Koichi Yuki,⁎ Miho Fujiogi, and Sophia Koutsogiannaki Abstract In December 2019, a novel coronavirus, now named as SARS-CoV-2, caused a series of acute atypical respiratory diseases in […]
Imperfect Vaccination Can Enhance the Transmission of Highly Virulent Pathogens
Authors: Andrew F. Read ,Susan J. Baigent,Claire Powers,Lydia B. Kgosana,Luke Blackwell,Lorraine P. Smith,David A. Kennedy,Stephen W. Walkden-Brown,Venugopal K. Nair Abstract Could some vaccines drive the evolution of more virulent pathogens? Conventional […]
How To Increase Platelet Count In COVID Patients? What Is Thrombocytopenia?
Authors: Ananya Varma Platelets are said to play an important role in inflammatory signalling. Here is why it is important to keep a check of Platelet count in COVID patients. Given […]