Category: Respiratory Syndrome

Mesenteric thrombosis in patients with coronavirus disease: comprehensive assessment and treatment

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Authors: A.R. Stasyshyn , .S. Stadnyk, A.I. Doroshak,I et. al., (Medical perspectives) 27(1):86-91 DOI:10.26641/2307-0404.2022.1.254332 Abstract Acute mesenteric circulatory disorder belongs to the most serious diseases of the abdominal cavity. Being an emer­gency condition, it is associated with high mortality. Coronavirus infection is an anthroponotic disease in the group of acute respiratory infections, is characterized by damage […]

Pathophysiological, immunological, and inflammatory features of long COVID

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Karen Bohmwald1,2†Benjamín Diethelm-Varela1†Linmar Rodríguez-Guilarte1 , et. al., Front. Immunol., 27 February 2024, Sec. Viral Immunology, Volume 15 – 2024 | https://doi.org/10.3389/fimmu.2024.1341600 The COVID-19 pandemic continues to cause severe global disruption, resulting in significant excess mortality, overwhelming healthcare systems, and imposing substantial social and economic burdens on nations. While most of the attention and therapeutic efforts have […]

Long COVID: major findings, mechanisms and recommendations

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Hannah E. Davis, , Lisa McCorkell, Julia Moore Vogel, Eric J. Topol Nature Reviews Microbiology volume 21, pages133–146 (2023)Cite this article Abstract Long COVID is an often debilitating illness that occurs in at least 10% of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections. More than 200 symptoms have been identified with impacts on multiple organ systems. At least 65 million individuals […]

Endothelial thrombomodulin downregulation caused by hypoxia contributes to severe infiltration and coagulopathy in COVID-19 patient lungs

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Authors: Taejoon Won, Megan K. Wood, David M. Hughes, Monica V. Talor, Zexu Ma Jowaly Schneider, et al. Published:January 12, 2022DOI:https://doi.org/10.1016/j.ebiom.2022.103812 Background Thromboembolism is a life-threatening manifestation of coronavirus disease 2019 (COVID-19). We investigated a dysfunctional phenotype of vascular endothelial cells in the lungs during COVID-19. Methods We obtained the lung specimens from the patients […]

How does coronavirus kill? Clinicians trace a ferocious rampage through the body, from brain to toes

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Authors: By Meredith Wadman, Jennifer Couzin-Frankel, Jocelyn Kaiser, Catherine MatacicApr. 17, 2020 , 6:45 PM On rounds in a 20-bed intensive care unit one recent day, physician Joshua Denson assessed two patients with seizures, many with respiratory failure and others whose kidneys were on a dangerous downhill slide. Days earlier, his rounds had been interrupted as his team tried, […]

Histopathological observations in COVID-19: a systematic review

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Authors: Vishwajit Deshmukh1, Rohini Motwani, Ashutosh Kumar3, Chiman Kumari4, Khursheed Raza5 Correspondence to Dr Rohini Motwani, Department of Anatomy, ESIC Medical College and Hospital, Sanathnagar, Hyderabad, Telangana, India; rohinimotwani@gmail.com Abstract Background Coronavirus disease-2019 (COVID-19) has caused a great global threat to public health. The World Health Organization (WHO) has declared COVID-19 disease as a pandemic, affecting the human respiratory and other […]

COVID-19 pathophysiology: A review

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Authors: COVID-19 pathophysiology: A review Koichi Yuki,⁎ Miho Fujiogi, and Sophia Koutsogiannaki Abstract In December 2019, a novel coronavirus, now named as SARS-CoV-2, caused a series of acute atypical respiratory diseases in Wuhan, Hubei Province, China. The disease caused by this virus was termed COVID-19. The virus is transmittable between humans and has caused pandemic worldwide. The […]

What Does COVID Do to Your Blood?

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Authors: Panagis Galiatsatos, M.D., M.H.S., Robert Brodsky, M.D. COVID-19 is a very complex illness. The coronavirus that causes COVID-19 attacks the body in many different ways, ranging from mild to life threatening. Different organs and tissues of the body can be affected, including the blood. Robert Brodsky, a blood specialist who directs the Division of […]

Platelets Promote Thromboinflammation in SARS-CoV-2 Pneumonia

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Authors: Francesco Taus, Gianluca Salvagno, Stefania Canè, Cristiano Fava, Fulvia Mazzaferri, Elena Carrara, Varvara Petrova, Roza Maria Barouni, Francesco Dima, Andrea Dalbeni, Simone Romano, Abstract Objective: Pulmonary thrombosis is observed in severe acute respiratory syndrome coronavirus 2 pneumonia. Aim was to investigate whether subpopulations of platelets were programmed to procoagulant and inflammatory activities in coronavirus disease 2019 (COVID-19) patients with pneumonia, without comorbidities predisposing to […]