Exploring the Clinical Features, Management of Hypertension, and Predictors of Severity in Hospitalized Hypertensive COVID-19 Patients

Abstract Background Hypertension significantly contributes to the severity, prolonged hospitalization, the need for intensive care, and mortality of COVID-19 patients. However, the data is still evolving. This study investigated the predictors of severity among hypertensive COVID-19 patients. Methodology This cohort study included 333 hospitalized hypertensive COVID-19 patients at the Indus Hospital, Karachi, Pakistan, from April […]

The Concealing Effect of COVID-19: Unveiling the Surge in Community-Acquired Infections and Its Association With Diabetic Ketosis During the Pandemic

Abstract Background Some studies suggest that the SARS-CoV-2 pandemic has contributed to diverting attention from other community-acquired infections (CAIs), leading to an increase in their incidence and severity. Our study aimed to describe and compare clinical features of CAI before and during the pandemic as a factor precipitating diabetes ketoacidosis (DKA). Methodology We included 250 […]

COVID-19, post-acute COVID-19 syndrome (PACS, “long COVID”) and post-COVID-19 vaccination syndrome Similarities and differences

Felix Scholkmann a,, Christian-Albrecht May University Hospital Zurich, University of Zurich, 8091 Zurich, Switzerland b Department of Anatomy, Faculty of Medicine Carl Gustav Carus, TU Dresden, 01307 Dresden, Germany ABSTRACT Worldwide there have been over 760 million confirmed coronavirus disease 2019 (COVID-19) cases, and over 13 billion COVID-19 vaccine doses have been administered as of […]

Mast cell activation in lungs during SARS-CoV-2 infection associated with lung pathology and severe COVID-19

Janessa Y.J. Tan,1 Danielle E. Anderson,2,3 Abhay P.S. Rathore,4 Aled O’Neill,1 Chinmay Kumar Mantri,1 Wilfried A.A. Saron,1 Cheryl Q.E. Lee,5 Chu Wern Cui,5 Adrian E.Z. Kang,1 Randy Foo,1 Shirin Kalimuddin,1,6 Jenny G. Low,1,6 Lena Ho,5 Paul Tambyah,7,8 Thomas W. Burke,9 Christopher W. Woods,9,10 Kuan Rong Chan,1 Jörn Karhausen,4,11 and Ashley L. St. John1,4,12,13 Published August 10, 2023 – 10.1172/JCI149834 Journal of Clinical Investigation Lung inflammation is a hallmark of Coronavirus disease 2019 (COVID-19) in patients […]

The intersection of COVID-19 and autoimmunity

Jason S. Knight,1 Roberto Caricchio,2 Jean-Laurent Casanova,3,4,5,6 Alexis J. Combes,7 Betty Diamond,8 Sharon E. Fox,9,10 David A. Hanauer,11 Judith A. James,12 Yogendra Kanthi,13 Virginia Ladd,14 Puja Mehta,15 Aaron M. Ring,16 Ignacio Sanz,17 Carlo Selmi,18,19 Russell P. Tracy,20 Paul J. Utz,21 Catriona A. Wagner,14 Julia Y. Wang,22 and William J. McCune1,Published October 28, 2021 – Free access | 10.1172/JCI154886 Acute COVID-19, caused by SARS-CoV-2, is characterized by diverse clinical presentations, ranging from asymptomatic infection to fatal respiratory […]

Systemic and organ-specific immune-related manifestations of COVID-19

Manuel Ramos-Casals, Pilar Brito-Zerón & Xavier Mariette Nature Reviews Rheumatology volume 17, pages315–332 (2021) Cite this article Abstract Immune-related manifestations are increasingly recognized conditions in patients with COVID-19, with around 3,000 cases reported worldwide comprising more than 70 different systemic and organ-specific disorders. Although the inflammation caused by SARS-CoV-2 infection is predominantly centred on the respiratory system, some patients can develop an […]

Large study provides scientists with deeper insight into long COVID symptoms

May 25, 2023, National Heart, Lung & Blood Institute NIH-funded research effort identifies most common symptoms, potential subgroups, and initial symptom-based scoring system – with aim of improving future diagnostics and treatment Initial findings from a study of nearly 10,000 Americans, many of whom had COVID-19, have uncovered new details about long COVID, the post-infection […]

Long Covid: MRI scans reveal new clues to symptoms

September 24, 2023 By Dominic Hughes, Health correspondent, BBC News People living with long Covid after being admitted to hospital are more likely to show some damage to major organs, according to a new study. MRI scans revealed patients were three times more likely to have some abnormalities in multiple organs such as the lungs, […]

COVID-19 can trigger auto-immune disorders-related antibodies, causing thrombosis and other complications

SEPTEMBER 12, 2023 by Maria Fernanda Ziegler, FAPESP Medical Express An article published in npj Aging reveals that natural production of auto-antibodies increases with age, and that infection by SARS-CoV-2 can exacerbate production of auto-antibodies relating to auto-immune diseases, helping to explain why aging increases the chances of developing severe COVID-19. The study also discovered some of the factors that […]

COVID Is Increasingly Looking Like a Cold or Flu

Friday, 22 September 2023 Newsmax Health Symptoms of mild COVID-19 infection have shifted this season, and now are more akin to those of allergies and the common cold, doctors say. Many people with COVID-19 now are presenting with upper respiratory symptoms like runny nose, watery eyes and a sore throat, said Dr. Teresa Lovins, an independent […]