Authors: Monia Marchetti 1 COVID-19 pandemia is a major health emergency causing hundreds of deaths worldwide. The high reported morbidity has been related to hypoxia and inflammation leading to endothelial dysfunction […]
Increased complement activation is a distinctive feature of severe SARS-CoV-2 infection
Authors: Lina Ma1, View ORCID ProfileSanjaya K. Sahu1, View ORCID ProfileMarlene Cano1, Vasanthan Kuppuswamy2, Jamal Bajwa1,3, View ORCID ProfileJa’Nia McPhatter1,4 Complement activation has been implicated in the pathogenesis of severe SARS-CoV-2 infection. However, it remains […]
Sars cov 2 drives jak1 2 dependent local complement hyperactivation
Authors: Patients with coronavirus disease 2019 (COVID-19) present a wide range of acute clinical manifestations affecting the lungs, liver, kidneys and gut. Angiotensin converting enzyme (ACE) 2, the best-characterized entry […]
Biden team’s misguided and deadly COVID-19 vaccine strategy
Vaccination ‘arms race’ could prove dangerous to the American public Authors: Dr. Robert Malone and Peter Navarro The Biden administration’s strategy to universally vaccinate in the middle of the pandemic […]
Complement control for COVID-19
Authors: Markus Bosmann1,2,3,4,* The complement system is an integral part of innate immune defense. It consists of about 50 proteins in plasma, on cell surfaces, and inside host cells. The […]
SARS-CoV-2 spike protein-mediated cell signaling in lung vascular cells
Authors: Yuichiro J. Suzuki,a,⁎ Sofia I. Nikolaienko,b Vyacheslav A. Dibrova,b Yulia V. Dibrova,b Volodymyr M. Vasylyk,c Mykhailo Y. Novikov,d Nataliia V. Shults,a and Sergiy G. Gychkab Currently, the world is suffering from the pandemic of coronavirus disease 2019 […]
COVID-19 vaccines induce severe hemolysis in paroxysmal nocturnal hemoglobinuria
Authors: Gloria F. Gerber,1 Xuan Yuan,1 Jia Yu,1 Benjamin A.Y. Cher,2 Evan M. Braunstein,1 Shruti Chaturvedi,1 and Robert A. Brodsky1,* Complement has emerged as a likely driver of the immune response and end-organ damage in COVID-19. In […]
Review the safety of Covid-19 mRNA vaccines: a review
Authors: Pratibha Anand 1, Vincent P Stahel 2 Abstract The novel coronavirus disease 2019 (COVID-19) has infected more than 100 million people globally within the first year of the pandemic. With a death […]
Safety of SARS-CoV-2 vaccines: a systematic review and meta-analysis of randomized controlled trials
Authors: Musha Chen, Yue Yuan, Yiguo Zhou, Zhaomin Deng, Jin Zhao, Fengling Feng, Huachun Zou & Caijun Sun Background Various modalities of vaccines against coronavirus disease 2019 (COVID-19), based on different platforms and immunization procedures, have been successively […]
COVID-19 Vaccine Safety in Adolescents Aged 12–17 Years — United States, December 14, 2020–July 16, 2021
Authors: Anne M. Hause, PhD1; Julianne Gee, MPH1; James Baggs, PhD1; Winston E. Abara, MD1; Paige Marquez, MSPH1; Deborah Thompson, MD2; John R. Su, MD, PhD1; Charles Licata, PhD1; Hannah […]