Category: Hypoxia

Pathological findings in organs and tissues of patients with COVID-19: A systematic review

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Authors: Sasha Peiris 1 2, Hector Mesa 3, Agnes Aysola 4, Juan Manivel 5, Joao Toledo 1 2, Marcio Borges-Sa 6, Sylvain Aldighieri 1 2, Ludovic Reveiz 2 7 Abstract Background: Coronavirus disease (COVID-19) is the pandemic caused by SARS-CoV-2 that has caused more than 2.2 million deaths worldwide. We…[...]

Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) and coronavirus disease 19 (COVID-19) – anatomic pathology perspective on current knowledge

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Authors: Sambit K. Mohanty, Abhishek Satapathy, Machita M. Naidu, Sanjay Mukhopadhyay, Shivani Sharma, Lisa M. Barton, Edana Stroberg, Eric J. Duval, Dinesh Pradhan, Alexandar Tzankov & Anil V. Parwani  Abstract Background The world is currently witnessing a major devastating pandemic of…[...]

COVID-19-driven endothelial damage: complement, HIF-1, and ABL2 are potential pathways of damage and targets for cure

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Authors: Monia Marchetti 1 COVID-19 pandemia is a major health emergency causing hundreds of deaths worldwide. The high reported morbidity has been related to hypoxia and inflammation leading to endothelial dysfunction…[...]