Researchers have sequenced the most comprehensive map of the SARS-CoV-2 genome yet


Authors: Anne Trafton MIT News First Published May 17, 2021 In early 2020, a few months after the Covid-19 pandemic began, scientists were able to sequence the full genome of SARS-CoV-2, the virus that causes the Covid-19 infection. While many of its genes were already known at that point, the full complement of protein-coding genes […]

Understanding COVID-19 through genome-wide association studies


Authors: Tom H. Karlsen  Nature Genetics volume 54, pages368–369 (2022)Cite this article 8742 Accesses 1 Citations 87 Altmetric Defining the most appropriate phenotypes in genome-wide association studies of COVID-19 is challenging, and two new publications demonstrate how case-control definitions critically determine outcomes and downstream clinical utility of findings. Exploring self-reported data from more than 700,000 participants in a direct-to-consumer ancestry genetics […]

COVID-19 outcomes and the human genome


Authors: Michael F. Murray MD, Eimear E. Kenny PhD, Marylyn D. RitchiePhD, Daniel J. Rader MD, Allen E. Bale MD, Monica A. Giovanni MS, CGC & Noura S. Abul-Husn MD, PhD Genetics in Medicine  volume 22, pages1175–1177 BACKGROUND In the COVID-19 pandemic, the opportunity to link host genomic factors to the highly variable clinical manifestations of SARS-CoV-2 infection has been widely recognized.1,2 The overt motivation for […]

COVID-19 alters human genes, explaining mystery behind coronavirus ‘long haulers’


Authors: Chris Melore Published APRIL 28, 2021 Study Finds For some COVID-19 patients, getting over their infection is just the beginning of the recovery. Over the last year, COVID “long haulers” have continued experiencing a variety of symptoms months after the virus clears. These include anything from skin problems, to shortness of breath, to losing […]

Chair of Lancet COVID-19 Commission: Investigate Origins of COVID


Authors: Michelle Edwards -May 24, 2022 The Chairman of The Lancet’s COVID-19 Commission has called for an independent inquiry into the origins of the SARS-CoV-2 virus. Jeffrey Sachs, a world-renowned economics professor, stated on May 19 that U.S. laboratory experiments may have contributed to the emergence of COVID-19. In an argument published in PNAS, a peer-reviewed journal of […]

Whole genome sequencing reveals host factors underlying critical Covid-19


Authors: Athanasios Kousathanas, Erola Pairo-Castineira, J. Kenneth BaillieArticle Published: 07 March 2022 nature  articles  article We are providing an unedited version of this manuscript to give early access to its findings. Before final publication, the manuscript will undergo further editing. Please note there may be errors present which affect the content, and all legal disclaimers apply. Abstract Critical Covid-19 is […]

STUDY: PFIZER VACCINE FUSES WITH HUMAN DNA IN THE LIVER: CAUTION


Authors: Jules Gomes  •  ChurchMilitant.com  •  March 2, 2022  The mRNA from Pfizer’s COVID-19 vaccine converts into DNA within six hours of entering the body’s liver cells according to a groundbreaking study by Swedish researchers at Lund University.  The explosive peer-reviewed research demolishes countless assertions by the “fact-checkers” and global health organizations. Fact-Checkers Caught UNICEF, for example, asserted that “mRNA vaccines are not […]

Close relatives of MERS-CoV in bats use ACE2 as their functional receptors


Authors: Qing Xiong,  View ORCID , , ei Cao,  Chengbao Ma,  Chen Liu, Junyu Si,  Peng Liu,  Mengxue Gu,  Chunli Wang, Lulu Shi, Fei Tong, Meiling Huang, Jing Li, Chufeng Zhao,  Chao Shen,   Yu Chen,   Huabin Zhao,  Ke Lan,  Xiangxi Wang,  Huan Yan Summary Middle East Respiratory Syndrome coronavirus (MERS-CoV) and several bat coronaviruses employ Dipeptidyl peptidase-4 (DPP4) as their functional receptors1–4. However, the receptor for NeoCoV, the closest MERS-CoV relative yet discovered in bats, remains enigmatic5. In this study, we unexpectedly found that […]

The Epidemiology, Transmission, and Diagnosis of COVID-19


Authors: By: Neesha C. Siriwardane & Rodney Shackelford, DO, Ph.D. April 15, 2020 Introduction to COVID-19 Coronaviruses are enveloped single-stranded RNA viruses of the Coronaviridae family and order Nidovirales (1). The viruses are named for their “crown” of club-shaped S glycoprotein spikes, which surround the viruses and mediate viral attachment to host cell membranes (1-3). Coronaviruses are found in domestic […]

The origin of SARS-CoV-2 furin cleavage site remains a mystery


Authors: By Dr. Liji Thomas, MD Feb 17 2021 The ongoing pandemic of coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has largely defied attempts to contain its spread by non-pharmaceutical interventions (NPIs). With the massive loss of life and economic damage, the only way out, in the absence of […]