Foundations of Peripheral Blood Biomarker Signatures and Immune Stratification John Murphy, M.D., M.P.H., D.P.H, President, COVID-19 Long-haul Foundation Summary Post–acute sequelae of SARS-CoV-2 infection (PASC), commonly termed Long COVID, is […]
Long-COVID Brain Fog: Reconsidering the Centrality of Ongoing Neuroinflammation
A Mechanistic Reappraisal of Cognitive Dysfunction Following SARS-CoV-2 Infection Author: John Murphy, CEO, COVID-19 Long-haul Foundation Abstract “Brain fog” in Long COVID has often been attributed to persistent neuroinflammation driven […]
Long-COVID: assessment of circulating markers suggests no cerebral neuronal damage, neuroinflammation or systemic inflammation–a controlled study
Roald Omdal, Ole Bernt Lenning, Grete Jonsson, Scientific Reports , Article number: (2026) Cite this article We are providing an unedited version of this manuscript to give early access to its findings. Before final publication, the manuscript […]
Scientists detect virus traces in blood that may unlock long COVID’s mystery
Scientists have found protein fragments from the COVID-19 virus hidden inside tiny cellular packages in the blood of long COVID patients, offering the first potential measurable biomarker for the condition. […]
OPG and TNFR1 as Potential Biomarkers of Inflammation in Older Adults with Acute COVID-19
Ramon-Luing LA , Flores-Gonzalez J , Cataneo-Piña DJ, et. al., DOI https://doi.org/10.2147/JIR.S545926 Background: Older individuals are at high risk for severe COVID-19 and often experience geriatric syndromes as post-COVID-19 sequelae associated with inflammation. Osteoprotegerin (OPG) and Tumor […]
Researchers have identified a potential biomarker for long COVID.
If the findings of their study are confirmed by other research centers, the biomarker could be the first specific and quantifiable indicator for confirming long COVID. Currently, clinicians confer a […]
Microclot Formation and Fibrinolytic Resistance in Long COVID: Mechanisms, Biomarkers, and Visualization
Author: John Murphy, President, COVID-19 Long-haul Foundation Abstract Long COVID, or post-acute sequelae of SARS-CoV-2 infection (PASC), has emerged as a chronic multisystem condition affecting millions globally. Among its most […]
Diagnostic Biomarkers and Imaging Modalities in Long COVID: Toward Precision Detection and Monitoring
Author: John Murphy, President, COVID-19 Long-haul Foundation Abstract Long COVID, or post-acute sequelae of SARS-CoV-2 infection (PASC), presents with a complex array of symptoms affecting multiple organ systems. Accurate diagnosis […]
COVID Research Gaps and Future Directions: Standardization, Longitudinal Recovery, AI-Driven Biomarkers, and Policy Reform
Author: John Murphy, President, COVID-19 Long-haul Foundation Abstract Long COVID, or post-acute sequelae of SARS-CoV-2 infection (PASC), remains a poorly defined and under-researched condition affecting millions globally. Despite its prevalence, […]
Transcriptomic analysis reveals shared deregulated neutrophil responses in COVID-19 and idiopathic pulmonary fibrosis
Abstract Background Coronavirus disease 2019 (COVID-19) is a respiratory disease linked with deregulated immune responses, leading to hyperinflammation, acute respiratory distress syndrome, and pulmonary fibrosis, often with fatal outcomes. Neutrophils […]