John Murphy, M.D., MPH, D.P.H., President The COVID19 Long-haul Foundation AbstractA growing body of evidence implicates mitochondrial dysfunction — including depletion of mitochondrial DNA (mtDNA), loss of mitochondrial membrane potential, […]
COVID Fatigue: Etiology, Genomics, Physiology, Pathology, Neurobiology, Sleep Disturbance, Treatment, and Prognosis
John Murphy, CEO COVID-19 Long-haul Foundation Abstract Fatigue is the most prevalent and disabling symptom among survivors of SARS‑CoV‑2 infection, persisting in a substantial proportion of patients months to years […]
COVID-19 and Cataractogenesis: Mechanistic Insights into Viral-Induced Ocular Pathology
Abstract Cataracts, the leading cause of blindness worldwide, are traditionally associated with aging, oxidative stress, and metabolic disorders. However, emerging evidence suggests that SARS-CoV-2 infection may accelerate or precipitate cataract […]
Exploring DNA methylation, telomere length, mitochondrial DNA, and immune function in patients with Long-COVID
Andrea Polli, Lode Godderis, Dries S. Martens, et. al., , BMC Medicine volume 23, Article number: 60 (2025) Cite this article Abstract Background Long-COVID is defined as the persistency or development of new symptoms 3 months after the initial SARS-CoV-2 […]
Long Covid: Hormone Imbalances and/or Rather Complex Immune Dysregulations?
Christian A Koch, Journal of the Endocrine Society, Volume 8, Issue 5, May 2024, bvae043, https://doi.org/10.1210/jendso/bvae043 Commentary Approximately 5% of all individuals infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) […]
Long COVID and brain inflammation: unravelling mechanisms and potential therapies
Fatemeh Saheb Sharif-Askari1,2*†Jacob Raber3*†Karem H. Alzoubi1,2 Patients with Long COVID often experience persistent brain-related symptoms, including brain fog, mood changes, and dizziness (1–3), likely driven by neuroinflammation even after the […]
🧪 COVID Spike Protein and Kidney Damage: Stage 3B Illness, Fluid Retention, and Electrolyte Recovery
As research into Long COVID and post-vaccination syndromes deepens, 2025 peer-reviewed studies have identified a troubling link between spike protein persistence and kidney damage, particularly in patients progressing to Stage […]
Scientists discover why long COVID makes patients so tired
StudyFinds Analysis AMSTERDAM, Netherlands — A new study is revealing the physical cause behind the persistent fatigue long COVID-19 patients experience. Researchers from Amsterdam University Medical Center (UMC) and Vrije Universiteit […]
Long COVID: damaged mitochondria in muscles might be linked to some of the symptoms
Caroline Dalton, Associate Professor of Neuroscience and Genetics, Sheffield Hallam University It’s estimated around 3% of people in the UK experience long COVID – persistent, long-lasting symptoms after a COVID-19 infection. Long […]
The first major set of genetic associations found in long COVID
PrecisionLife’s Dr Sayoni Das, a computational biologist who leads the research and development of bioinformatics pipelines that generate biological insights from PrecisionLife’s core technology and support drug discovery programs, details […]