Category: interferon λ1 (IFN-λ1)

Human SARS-CoV-2 challenge uncovers local and systemic response dynamics

Posted on | Posted on John Murphy | Leave a Comment on Human SARS-CoV-2 challenge uncovers local and systemic response dynamics

Rik G. H. Lindeboom, Kaylee B. Worlock, Lisa M. Dratva, et. al.Nature (2024) Abstract The COVID-19 pandemic is an ongoing global health threat, yet our understanding of the dynamics of early cellular responses to this disease remains limited1. Here in our SARS-CoV-2 human challenge study, we used single-cell multi-omics profiling of nasopharyngeal swabs and blood to temporally resolve abortive, […]

Potential Prophylactic Treatments for COVID-19

Posted on | Posted on John Murphy | Leave a Comment on Potential Prophylactic Treatments for COVID-19

Noam Ben-Zuk,1,† Ido-David Dechtman,2,3,† Itai Henn,1 Libby Weiss,1 Amichay Afriat,4 Esther Krasner,1,* and Yoav Gal1,5,*Kenneth Lundstrom, Academic Editor and Alaa A. A. Aljabali, Academic Editor Viruses. 2021 Jul; 13(7): 1292. Published online 2021 Jul 2. doi: 10.3390/v13071292 PMCID: PMC8310088 PMID: 34372498 Abstract The World Health Organization declared the SARS-CoV-2 outbreak a Public Health Emergency of International Concern at the end of January 2020 and a pandemic two months later. The […]

New Clues To Long Covid: Prolonged Inflammatory Response

Posted on | Posted on John Murphy | Leave a Comment on New Clues To Long Covid: Prolonged Inflammatory Response

Authors: William A. Haseltine January 2922 Posted July 2022 Forbes For many Covid-19 patients, the end of the acute stage of infection is only the beginning of another difficult experience: Long Covid. Defined by the persistence of physical and neuropsychiatric symptoms over a period of 12 weeks or longer, the exact causes of long Covid […]