John Murphy, CEO, The COVID-19 Long Haul Foundation Abstract SARS-CoV-2 infection has been associated with delayed nail abnormalities including Beau’s lines, onychomadesis, transverse leukonychia, and chromonychia (“COVID nails”). These manifestations […]
Chronic Inflammation Pathways Identified in Long COVID
I. Persistent Cytokine-Driven Inflammatory Signaling I.A. IL-6–Centered Inflammatory Axis Interleukin-6 (IL-6) has emerged as one of the most consistently elevated cytokines in Long COVID cohorts, serving as a central node […]
COVID Fatigue: Etiology, Genomics, Physiology, Pathology, Neurobiology, Sleep Disturbance, Treatment, and Prognosis
John Murphy, CEO COVID-19 Long-haul Foundation Abstract Fatigue is the most prevalent and disabling symptom among survivors of SARS‑CoV‑2 infection, persisting in a substantial proportion of patients months to years […]
🧠 Post-Acute Sequelae of SARS-CoV-2 Infection and Epstein-Barr Virus Reactivation
John Murphy, CEO The COVID-19 Long-haul Foundation 📄 Abstract Background: Post-acute sequelae of SARS-CoV-2 infection (PASC), commonly referred to as long COVID, is characterized by persistent symptoms beyond 12 weeks […]
Diagnostic Biomarkers and Imaging Modalities in Long COVID: Toward Precision Detection and Monitoring
Author: John Murphy, President, COVID-19 Long-haul Foundation Abstract Long COVID, or post-acute sequelae of SARS-CoV-2 infection (PASC), presents with a complex array of symptoms affecting multiple organ systems. Accurate diagnosis […]
Why Long COVID Causes Shortness of Breath—and What We’re Learning to Do About It
Author: John Murphy Affiliation: COVID-19 Long-haul Foundation 🌬️ Introduction: When Breathing Doesn’t Bounce Back For many people recovering from COVID-19, the virus doesn’t simply go away. Weeks or months later, […]
🧠 Long COVID and Edema: A 2025 Clinical Overview
📚 Background and Etiology Long COVID, or post-acute sequelae of SARS-CoV-2 infection (PASC), affects 10–30% of individuals post-infection, with symptoms persisting beyond three months. Edema—fluid accumulation in tissues—has emerged as […]
Respiratory Viruses Like Flu Or COVID Could Cause ‘Sleeping’ Cancer Cells To Wake Up
StudyFinds Analysis, Steve Fink In A Nutshell AURORA, Colo. — Common respiratory infections like the flu and COVID-19 might jolt dormant cancer cells back to life in survivors, causing them to multiply […]
🩸 COVID-19 and Blood Morphology: Insights from 2025 Peer-Reviewed Research
As the global understanding of COVID-19 deepens, 2025 research has illuminated how SARS-CoV-2 affects blood morphology, particularly red blood cells (RBCs), hemoglobin function, and hematopoiesis. These changes are not only […]
Sudden Sleep Collapse: A Long-COVID Nightmare
Long COVID can trigger sudden collapses in consciousness or overwhelming sleepiness through a mix of neurological, immunological, and autonomic dysfunctions. Here’s how the body gets hijacked into shutdown mode: 🧠 […]