By Theo Farrant New research offers what scientists describe as the first biological evidence of Long COVID brain fog. Scientists in Japan have identified a potential biological cause of Long COVID brain fog, […]
Chronic Inflammation Pathways Identified in Long COVID
I. Persistent Cytokine-Driven Inflammatory Signaling I.A. IL-6–Centered Inflammatory Axis Interleukin-6 (IL-6) has emerged as one of the most consistently elevated cytokines in Long COVID cohorts, serving as a central node […]
Inflammatory Markers as Predictors of Onset and Recovery of Olfactory and Gustatory Dysfunction in COVID-19 Patients
Burak Celik • Fatih Gul • Hacı Huseyin Dere, DOI: 10.7759/cureus.96003 Abstract Background Olfactory and gustatory dysfunctions are widely recognized as characteristic manifestations of COVID-19. However, the relationship between disease severity, inflammatory markers, and the […]
Inflammation: The Molecular Convergence of Gout, COVID-19, and Uric Acid Metabolism
Inflammation is not merely a symptom—it is a biological imperative. It orchestrates the body’s defense against infection, injury, and metabolic imbalance. Yet when dysregulated, inflammation becomes a crucible for chronic […]
Endothelial Dysfunction and Spike Protein Persistence in Long COVID: Mechanisms, Vulnerabilities, and Clinical Evidence
Author: John Murphy, President, COVID-19 Long-haul Foundation Abstract Long COVID, or post-acute sequelae of SARS-CoV-2 infection (PASC), is characterized by persistent symptoms affecting multiple organ systems. Among its most compelling […]
Transcriptomic analysis reveals shared deregulated neutrophil responses in COVID-19 and idiopathic pulmonary fibrosis
Abstract Background Coronavirus disease 2019 (COVID-19) is a respiratory disease linked with deregulated immune responses, leading to hyperinflammation, acute respiratory distress syndrome, and pulmonary fibrosis, often with fatal outcomes. Neutrophils […]
Ivermectin: A Multifaceted Drug With a Potential Beyond Anti-parasitic Therapy
Baneet Kaur • Cyril Blavo • Mayur S. Parmar, DOI: 10.7759/cureus.56025 Abstract Ivermectin was first discovered in the 1970s by Japanese microbiologist Satoshi Omura and Irish parasitologist William C. Campbell. Ivermectin has become a versatile […]
Effects of Non-invasive Vagus Nerve Stimulation on Inflammatory Markers in COVID-19 Patients: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Amira Mohamed Taha • Amr Elrosasy • Ahmed S. Mohamed •et.al. DOI: 10.7759/cureus.70613 Abstract The international healthcare community has encountered several difficulties because of the COVID-19 pandemic brought on by SARS-CoV-2. COVID-19 can lead to an […]
Inflammatory and Coagulation Marker Changes -Treated COVID-19 Patients
Akinari Tsukada • Daisuke Katagiri • Shinyu Izumi et. al., DOI: 10.7759/cureus.78836 Abstract Introduction Direct hemoperfusion using polymyxin B-immobilized polystyrene fiber column (PMX-DHP) removes endotoxin and inflammatory mediators from the blood. This study aimed to evaluate […]
A Pilot Case-Control Study of Muscle and Bone Health Status in Patients Who Have Recovered From COVID-19 Infection
Shital Bhor • Dipali Ladkat • Nikhil Shah • Ketan Gondhalekar • Piyush Chaudhari • Anuradha Khadilkar, DOI: 10.7759/cureus.76283 Abstract Background: Coronavirus disease 2019 (COVID-19), resulting from the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), affects various bodily systems, including […]