Category: Liver

Clinical update on risks and efficacy of anti-SARS-CoV-2 vaccines in patients with autoimmune hepatitis and summary of reports on post-vaccination liver injury

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Authors: Ana Lleo 1, Nora Cazzagon 2, Cristina Rigamonti 3, Giuseppe Cabibbo 4, Quirino Lai 5, Luigi Muratori 6, Marco Carbone 7, Italian Association for the Study of the LiverAffiliations expand PMID: 35410851 PMCID: PMC8958090DOI: 10.1016/j.dld.2022.03.014 Published:March 27, 2022DOI:https://doi.org/10.1016/j.dld.2022.03.014 Abstract Patients with liver diseases, especially those with cirrhosis, have an increased mortality risk when infected by SARS-CoV-2 and therefore anti-SARS-CoV-2 vaccine has been recommended by leading Scientific Associations for all patients with chronic […]

A Case of Hepatotoxicity After Receiving a COVID-19 Vaccine

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Authors: Muath M. Alqarni, Ammar Z. Faloudah, Amjad S. Alsulaihebi, Hassan K. Halawani, Abdulmajeed S. Khan Published: December 16, 2021  DOI: 10.7759/cureus.20455 Abstract The coronavirus disease 2019 (COVID-19) has led to a global health crisis. Its clinical manifestations are well-documented, and severe complications among patients who survived the infection are being continuously reported. Several vaccines with well-established efficacies and excellent safety […]

Autoimmune hepatitis after SARS-CoV-2 vaccine: New-onset or flare-up?

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Authors: Enver Avci 1, Fatma Abasiyanik 2 Autoimmune 2021 Dec;125: 102745. doi: 10.1016/j.jaut.2021.102745  Epub 2021 Nov 11. PMID:  34781161PMCID: PMC8580815DOI: 10.1016/j.jaut.2021.102745 Abstract Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has been reported to trigger several autoimmune diseases. There are also recent reports of autoimmune diseases that develop after SARS-CoV-2 vaccines. Autoimmune hepatitis is a polygenic multifactorial disease, which is diagnosed […]

Acute hepatitis with autoimmune features after COVID-19 vaccine: coincidence or vaccine-induced phenomenon?

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Authors: José M Pinazo-Bandera 1, Alicia Hernández-Albújar 1, Ana Isabel García-Salguero 2,  Isabel Arranz-Salas 2, Raúl J Andrade 1 3, Mercedes Robles-Díaz 1 3 Gastroenterol Rep (Oxf) 2022 Apr 27;10:goac014. doi: 10.1093/gastro/goac014. eCollection 2022. Introduction Autoimmune diseases result from a breach of immunological self-tolerance and tissue damage by autoreactive T lymphocytes. Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection is characterized by an inflammatory dysregulation that has been associated with […]

Liver injury following SARS-CoV-2 vaccination: A multicenter case series

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Authors: Hersh Shroff,1,∗Sanjaya K. Satapathy,2James M. Crawford,3Nancy J. Todd,4 and Lisa B. VanWagner1 J Hepatol. 2022 Jan  10.1016/j.jhep.2021.07.024 PMCID: PMC8324396PMID:  34339763 In response to the COVID-19 pandemic, two novel mRNA-based vaccinations against the SARS-CoV-2 virus have been manufactured and distributed in an unprecedented fashion. In light of their rapid uptake, providers must remain vigilant in their monitoring of new […]

Safety and Immunogenicity of SARS-CoV-2 Vaccines in Patients With Chronic Liver Diseases (CHESS-NMCID 2101): A Multicenter Study

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Authors: Jingwen Ai 1, Jitao Wang 2, Dengxiang Liu 3, Huiling Xiang 4, Ying Guo 5, Jet.al. Abstract Background & aims: We aimed to assess the safety and immunogenicity of inactivated whole-virion severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccines in patients with chronic liver diseases (CLD) in this study. Methods: This was a prospective, multi-center, open-label study. Participants aged over 18 years with confirmed CLD and […]

DC Investigating 109 Mysterious Hepatitis Cases In Children, Including 5 Deaths

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Authors: Jack Phillips via The Epoch Times, May 7, 2022 The U.S. Centers for Disease Control and Prevention (CDC) is investigating more than 100 cases of a mysterious form of hepatitis in children, saying that five have died so far. Dr. Jay Butler, the CDC’s deputy director of infectious diseases, said during a briefing said the agency […]

Japan reports first case of mysterious children’s liver disease as health experts explore possible Covid links

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Authors: Karen Gilchrist PUBLISHED TUE, APR 26 2022 CNBC KEY POINTS Japan has detected its first probable case of a mysterious liver disease that has so far affected over 170 children, largely in Britain. Health experts are exploring its possible links to Covid-19 or a common virus known as adenovirus. Of those infected, one child […]

SARS-CoV-2 Infection and the Liver

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Authors: Katie Morgan,1,*Kay Samuel,2Martin Vandeputte,1Peter C. Hayes,1 and John N. Plevris1 Pathogens. 2020 Jun; 9(6): 430.Published online 2020 May 30. doi: 10.3390/pathogens9060430 PMCID: PMC7350360PMID: 32486188 Abstract A novel strain of coronoviridae (SARS-CoV-2) was reported in Wuhan China in December 2019. Initially, infection presented with a broad spectrum of symptoms which typically included muscle aches, fever, dry cough, and shortness of breath. SARS-CoV-2 […]

Prevalence of organ impairment in Long COVID patients 6 and 12 months after initial symptoms

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Authors:  Pooja Toshniwal PahariaMar 24 2022Reviewed by Danielle Ellis, B.Sc. In a recent study posted to the medRxiv* preprint server, researchers assessed the prevalence of organ impairment in long coronavirus disease 2019 (COVID-19) six months and a year post-COVID-19 at London and Oxford. Multi-organ impairment associated with long COVID-19 is a significant health burden. Standardized multi-organ evaluation […]