Authors: Roberto F. Nicosia,∗∗ Giovanni Ligresti,† Nunzia Caporarello,‡ Shreeram Akilesh,∗ and Domenico Ribatti§ Patients with coronavirus disease 2019 (COVID-19) who are critically ill develop vascular complications characterized by thrombosis of small, medium, and large vessels. […]
Endothelial dysfunction in COVID-19: Current findings and therapeutic implications
Authors: Matthias P Nägele 1, Bernhard Haubner 1, Felix C Tanner 1, Frank Ruschitzka 1, Andreas J Flammer 2 Coronavirus disease 2019 (COVID-19) increases the risk of several non-pulmonary complications such as acute myocardial injury, renal failure or thromboembolic […]
Covid-19: links between genes and disease severity
Authors: Bolzano research centre In March 2020, thousands of scientists around the world joined forces to investigate the questions at the forefront of the medical debate on the pandemic: what […]
Cytokine Storm in COVID-19—Immunopathological Mechanisms, Clinical Considerations, and Therapeutic Approaches: The REPROGRAM Consortium Position Paper
Authors: Sonu Bhaskar,1,2,3,* Akansha Sinha,1,4 Maciej Banach,1,5,6,7 Shikha Mittoo,1,8 Robert Weissert,1,9 Joseph S. Kass,1,10 Santhosh Rajagopal,1,11 Anupama R. Pai,1,12 and Shelby Kutty1,13,14 Cytokine storm is an acute hyperinflammatory response that may be responsible for critical illness in many conditions […]
SARS-CoV-2 infection: The role of cytokines in COVID-19 disease
Authors: Víctor J Costela-Ruiz 1, Rebeca Illescas-Montes 1, Jose M Puerta-Puerta 2, Concepción Ruiz 3, Lucia Melguizo-Rodríguez 1 COVID-19 disease, caused by infection with SARS-CoV-2, is related to a series of physiopathological mechanisms that mobilize a wide variety of […]
In the lab, scientists identify possible COVID-19 treatment
Authors: St. Jude Children’s Research Hospital The COVID-19 pandemic continues to cause significant illness and death while treatment options remain limited. St. Jude Children’s Research Hospital scientists have discovered a […]
Pathways in the Pathophysiology of Coronavirus 19 Lung Disease Accessible to Prevention and Treatment
Authors: Michael Eisenhut 1, Jae Il Shin 2 Background: In COVID 19 related lung disease, which is a leading cause of death from this disease, cytokines like tumor necrosis factor-alpha (TNF alpha) may be […]
COVID-19 Open Research Dataset
Full-text and metadata dataset of COVID-19 and coronavirus-related scholarly articles optimized for machine readability and made available for use by the global research community. In response to the COVID-19 pandemic, […]
COVID and the brain: researchers zero in on how damage occurs
Authors: Michael Marshall How COVID-19 damages the brain is becoming clearer. New evidence suggests that the coronavirus’s assault on the brain could be multipronged: it might attack certain brain cells […]
Taking a Closer Look at COVID-19’s Effects on the Brain
Authors: Dr. Francis Collins While primarily a respiratory disease, COVID-19 can also lead to neurological problems. The first of these symptoms might be the loss of smell and taste, while […]