Who Is Most at Risk for Long COVID?

Demographic, clinical characteristics offer hints for caregivers, policymakers By JAKE MILLER March 8, 2023 Research This article is part of Harvard Medical School’s continuing coverage of COVID-19. A new study of more than 800,000 people has found that in the U.S., COVID “long haulers” were more likely to be older and female, with more chronic conditions than people in […]

Interwoven challenges of covid-19, poor diet, and cardiometabolic health

BMJ 2023; 383 doi: https://doi.org/10.1136/bmj-2023-076810 (Published 09 October 2023)Cite this as: BMJ 2023;383:e076810Read the full collection: Food for Thought 2023 Carmen Piernas, senior research fellow,  Jordi Merino, associate professor ,Correspondence to: C Piernas Carmen Piernas and Jordi Merino argue that suboptimal diet and poor metabolic health aggravated the covid-19 pandemic and require greater attention to increase population resilience and reduce health inequalities The covid-19 pandemic […]

Clinical determinants of the severity of COVID-19: A systematic review and meta-analysis

Authors: Xinyang Li, Xianrui Zhong, Yongbo Wang, Xiantao Zeng, Ting Luo, Qing Liu  Published: May 3, 2021 Abstract Objective We aimed to systematically identify the possible risk factors responsible for severe cases. Methods We searched PubMed, Embase, Web of science and Cochrane Library for epidemiological studies of confirmed COVID-19, which include information about clinical characteristics […]

Overweight/obesity as the potentially most important lifestyle factor associated with signs of pneumonia in COVID-19

Authors: Vanessa Sacco ,Barbara Rauch ,Christina Gar,Stefanie Haschka,Anne L. Potzel,Stefanie Kern-Matschilles,Friederike Banning,Irina Benz,Mandy Meisel,Jochen Seissler,Andreas Lechner  Published: November 18, 2020 Abstract Objective The occurrence of pneumonia separates severe cases of COVID-19 from the majority of cases with mild disease. However, the factors determining whether or not pneumonia develops remain to be fully uncovered. We therefore explored the […]

COVID-19: A Mitochondrial Perspective

Authors: Pankaj Prasun 1 Coronavirus disease 2019 (COVID-19) is the worst public health crisis of the century. Although we have made tremendous progress in understanding the pathogenesis of this disease, a lot more remains to be learned. Mitochondria appear to be important in COVID-19 pathogenesis because of its role in innate antiviral immunity, as well as […]

Endothelial dysfunction in COVID-19: Current findings and therapeutic implications

Authors: Matthias P Nägele 1, Bernhard Haubner 1, Felix C Tanner 1, Frank Ruschitzka 1, Andreas J Flammer 2 Coronavirus disease 2019 (COVID-19) increases the risk of several non-pulmonary complications such as acute myocardial injury, renal failure or thromboembolic events. A possible unifying explanation for these phenomena may be the presence of profound endothelial dysfunction and injury. This review provides an overview on the […]