The I-TECH Randomized Clinical Trial February 18, 2022 Authors: Steven Chee Loon Lim, MRCP1; Chee Peng Hor, MSc2,3; Kim Heng Tay, MRCP4; et alAnilawati Mat Jelani, MMed5; Wen Hao Tan, MMed6; Hong Bee Ker, MRCP1; Ting Soo Chow, MRCP7; Masliza Zaid, MMed8; Wee Kooi Cheah, MRCP6; Han Hua Lim, MRCP9; Khairil Erwan Khalid, MRCP10; Joo Thye Cheng, MRCP2; Hazfadzila Mohd Unit, MRCP11; Noralfazita An, MMed12; Azraai Bahari Nasruddin, MRCP13; Lee Lee Low, MRCP14; Song Weng Ryan Khoo, MRCP15; Jia Hui Loh, MRCP16; Nor […]
Baricitinib for patients with severe COVID-19—time to change the standard of care?
AuthorsAlexander Supadya,c,d and Robert Zeiserb Lancet Respir Med. 2022 Feb 3doi: 10.1016/S2213-2600(22)00021-2 [Epub ahead of print]PMCID: PMC8813061PMID: 35123659 Mortality is high among patients with severe COVID-19 who require invasive mechanical ventilation (IMV) or extracorporeal membrane oxygenation (ECMO).1, 2 Therefore, […]
Nuts and bolts of COVID-19 associated coagulopathy: the essentials for management and treatment
Authors: Patrick J Lindsay, a Rachel Rosovsky, b Edward A Bittner, c and Marvin G. Chang c ABSTRACT Introduction COVID-19-associated coagulopathy (CAC) is a well-recognized hematologic complication among patients with severe COVID-19 disease, where macro- and micro-thrombosis can […]
COVID-19 targets human adrenal glands
Authors: Waldemar Kanczkowski. Katja Evert. Marlena Stadtmüller, Martina Haberecker, Laura Laks, Lan-Sun Chen, et al. Published:November 18, 2021DOI:https://doi.org/10.1016/S2213-8587(21)00291-6PlumX Metrics COVID-19 develops due to infection with SARS-CoV-2, which particularly in elderly […]
Arthritis drug reduces mortality in severe COVID-19, huge clinical trial finds
For hospitalized patients already taking other proven COVID-19 drugs, pill further reduces chance of death Authors: KAI KUPFERSCHMIDT 3 MAR 2022 1:20 PM Baricitinib, an oral drug that dampens an […]
Fighting COVID-19 with milk?
Authors: Elsevier As the COVID-19 pandemic continues to claim lives around the world, dairy scientists may have a surprising role to play. In a new report published in the Journal of […]
Potential pharmacologic treatments for COVID-19 smell and taste loss: A comprehensive review
Authors: Elnaz Khani,aSajad Khiali,aSamineh Beheshtirouy,a and Taher Entezari-Malekia,b,∗ Eur J Pharmacol. 2021 Dec 5; 912: 174582.Published online 2021 Oct 19. doi: 10.1016/ j.ejphar.2021.174582 PMCID: PMC8524700PMID: 34678243 Abstract The acute loss of taste and smell following COVID-19 […]
Colchicine: A Possible COVID-19 Long haul Cardiac Therapy
Last Updated: December 16, 2021 Last Updated: December 16, 2021 Colchicine is an anti-inflammatory drug that is used to treat a variety of conditions, including gout, recurrent pericarditis, and familial Mediterranean fever.1 Recently, […]
The Role of Colchicine in Pericardial Syndromes
Authors: George Lazaros 1, Massimo Imazio 2, Antonio Brucato 3, Charalambos Vlachopoulos 1, Emilia Lazarou 1, Dimitrios Vassilopoulos 4, Dimitris Tousoulis 1PMID: 29336245 DOI: 10.2174/1381612824666180116101823 Curr Pharm Des . 2018;24(6):702-709. doi: 10.2174/1381612824666180116101823. Abstract Background: Colchicine is an old drug originally employed for the treatment of inflammatory disorders […]
Colchicine Treatment for Recurrent Pericarditis
A Decade of Experience Authors: Y. Adler, Y. Finkelstein, J. Guindo, A. Rodriguez de la Serna, Y. Shoenfeld, A. Bayes-Genis, A. Sagie, A. Bayes de Luna and D. H. SpodickOriginally published2 Jun 1998 https://doi.org/10.1161/01.CIR.97.21.2183 Circulation. 1998;97:2183–2185 Abstract Background—The most […]