Matheus Guidini Lima • Francisco Pires • Leopoldo Mandic Ferreira Furtado, et. al. ,DOI: 10.7759/cureus.93758 Abstract Traumatic brain injury (TBI) is a significant worldwide public health concern and is among the top causes of death […]
Sex-Based and Genetic Vulnerabilities: Hormonal Modulation, IL-6 Polymorphisms, HLA Factors, and Personalized Medicine Implications
Author: John Murphy, President, COVID-19 Long-haul Foundation Abstract Long COVID, or post-acute sequelae of SARS-CoV-2 infection (PASC), presents with a striking female predominance and heterogeneous symptom profiles. Emerging evidence suggests […]
Neurological sequelae of long COVID: a comprehensive review of diagnostic imaging, underlying mechanisms, and potential therapeutics
Grant McGee Talkington, Paresh Kolluru, Timothy E. Gressett, et. al., Frontiers in Neurology One lingering effect of the COVID-19 pandemic created by SARS-CoV-2 is the emergence of Long COVID (LC), […]
Persistent SARS-CoV-2 Spike Protein: Genomic Modulation, Immune Dysregulation, and Impaired Antibody Maturation
Author: John Murphy, CEO COVID 19 Long-haul Foundation Abstract The SARS-CoV-2 spike glycoprotein, central to viral entry and the target of mRNA vaccine platforms, has emerged as a persistent antigen […]
Long-Term Outcomes and Mortality Risk: Cardiovascular Sequelae, Actuarial Modeling, and Public Health Implications
Author: John Murphy, President, COVID-19 Long-haul Foundation Abstract Long COVID, or post-acute sequelae of SARS-CoV-2 infection (PASC), has emerged as a chronic condition with significant long-term health consequences. This article […]
Post-Vaccination Spike Protein Migration: Genomic Mechanisms of Motility, Pathological Spread, and Long-Term Implications
Author: John Murphy, M.D. CEO Covid-19 Long-haul Foundation Abstract Messenger RNA (mRNA) vaccines have revolutionized infectious disease prevention, offering rapid deployment and robust immunogenicity. However, emerging evidence suggests that the […]
Microclot Formation and Fibrinolytic Resistance in Long COVID: Mechanisms, Biomarkers, and Visualization
Author: John Murphy, President, COVID-19 Long-haul Foundation Abstract Long COVID, or post-acute sequelae of SARS-CoV-2 infection (PASC), has emerged as a chronic multisystem condition affecting millions globally. Among its most […]
Genomic Convergence: Emerging Pathways, Mechanisms, and Druggable Targets in Precision Medicine for COVID Long-haul Research
Author: John Murphy, CEO COVID-19 Long-haul Foundation Abstract The past three years have witnessed an unprecedented acceleration in genomic discovery, driven by advances in single-cell sequencing, spatial transcriptomics, and integrative […]
🧬 Spike Protein Modifications: Scientific Possibilities
If a scientist were hypothetically attempting to modify the SARS-CoV-2 spike protein for enhanced function—whether for research, vaccine design, or malicious intent—there are specific genomic regions and tools they might […]
🧠 Neurovascular Dysregulation and Cognitive Impairment in Long COVID
Author: John Murphy, President, COVID-19 Long-haul Foundation Abstract Long COVID, or post-acute sequelae of SARS-CoV-2 infection (PASC), presents with a constellation of neurological symptoms including brain fog, memory loss, and […]