Long COVID: major findings, mechanisms and recommendations


Hannah E. Davis, , Lisa McCorkell, Julia Moore Vogel, Eric J. Topol Nature Reviews Microbiology volume 21, pages133–146 (2023)Cite this article Abstract Long COVID is an often debilitating illness that occurs in at least 10% of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections. More than 200 symptoms have been identified with impacts on multiple organ systems. At least 65 million individuals […]

Study points to vagus nerve dysfunction as a central pathophysiological feature of long COVID


by Emily Henderson, B.Sc.Feb 2022 News Medical Life Sciences New research to be presented at this year’s European Congress of Clinical Microbiology and Infectious Diseases (ECCMID 2022, Lisbon, 23-26 April) suggests that many of the symptoms connected to post-COVID syndrome (PCC, also known as long COVID) could be linked to the effect of the virus on […]

Vagus nerve dysfunction has a central pathogenic role in the pathophysiology of the post-COVID condition


By Neha Mathur, Jun 2023, The Lancet In a recent study posted to Preprints with The Lancet* server, a team of researchers performed an extensive database search to identify studies providing consistent data on structural and functional alterations in organs and body parts innervated by the vagus nerve in subjects with post-coronavirus disease 2019 (COVID-19) condition (PCC), […]

Long COVID Now Looks like a Neurological Disease, Helping Doctors to Focus Treatments


The causes of long COVID, which disables millions, may come together in the brain and nervous system BY STEPHANI SUTHERLAND Scientific American, 2023 Issue Neuroscience Tara Ghormley has always been an overachiever. She finished at the top of her class in high school, graduated summa cum laude from college and earned top honors in veterinary school. […]

Cardiorespiratory dysautonomia in post-COVID-19 condition: Manifestations, mechanisms and management


Artur Fedorowski, Monika Fagevik Olsén, Frida Nikesjö, Christer Janson, Judith Bruchfeld, Maria Lerm, Kristofer Hedma: May 2023, Journal of Internal MedicineVolume 294, Issue 5 p. 548-562 Abstract A significant proportion of COVID-19 patients experience debilitating symptoms for months after the acute infection. According to recent estimates, approximately 1 out of 10 COVID-19 convalescents reports persistent health issues more than 3 months after […]

What Is Dysautonomia?


By Carly Vandergriendt,  2023, Health Finds Dysautonomia is when your autonomic nervous system doesn’t work properly, usually due to an underlying condition. There are several types, including postural orthostatic tachycardia syndrome (POTS). Your autonomic nervous system (ANS) is responsible for functions that your body does without you having to think about them, such as pumping blood, […]

Dysautonomia and small fiber neuropathy in post-COVID condition and Chronic Fatigue Syndrome


N. Azcue, R. Del Pino, et. al., Journal of Translational Medicine volume 21, Article number: 814 (2023)  Abstract Background Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) and post-COVID condition can present similarities such as fatigue, brain fog, autonomic and neuropathic symptoms. Methods The study included 87 patients with post-COVID condition, 50 patients with ME/CFS, and 50 healthy controls (HC). The hemodynamic autonomic function was […]

Study finds 67% of individuals with long COVID are developing dysautonomia


By Shanet usan Alex, News Medical Life Sciences In a recent study posted to the medRxiv* preprint server, researchers analyzed the traits of autonomic symptom burden in long coronavirus disease (COVID). Study: Characterization of Autonomic Symptom Burden in Long COVID: A Global Survey of 2,314 Adults. This news article was a review of a preliminary scientific report that had […]

Breathing difficulties after covid-19: a guide for primary care


BMJ 2023; 381 doi: https://doi.org/10.1136/bmj-2023-074937 (Published 14 June 2023)Cite this as: BMJ 2023;381:e07493, Rachael Evans What you need to know Around one in four adults who were hospitalised with covid-19 and one in six who were not hospitalised experience persistent breathing difficulties beyond four weeks after SARS-CoV-2 infection,12 and a cohort study in China demonstrated that breathlessness can persist beyond two years.3 In long […]

Long Covid is hard — here are five tips to help


By Andrea Kane, CNN, November 9, 2023 (CNN) — Brain fog, fatigue, heart palpitations, post-exertional malaise and dizziness are a handful of the symptoms associated people with long Covid in adults. They are among the 12 symptoms identified as part of the National Institute of Health’s RECOVER initiative that can be reliably used to classify someone as having long […]