Etiology, pathology, genomics, physiology, and clinical course of post-SARS-CoV-2 autonomic disease John Murphy, CEO, The COVID-19 Long haul Foundation Abstract Autonomic dysfunction has emerged as one of the most reproducible […]
COVID-19 and Dysautonomia: From Vagal Injury to Systemic Physiological Failure
A narrative review of autonomic dysfunction, vagal disruption, pathophysiology and clinical course in Long COVID Abstract Background: Dysautonomia has emerged as one of the most consequential neurological and cardiovascular manifestations […]
Long Covid and Depression: Neuroinflammation, Systemic Illness, and the Persistence of Affective Dysfunction
John Murphy, CEO, The COVID-19 Long-haul Foundation Review Article Abstract Long Covid, or post–COVID-19 condition, has emerged as a heterogeneous, multisystem disorder that may persist for months or years after […]
Multidisciplinary Care Pathways for Long COVID Fatigue:
A Systems-Based Model Integrating Rehabilitation Medicine, Neuroimmunology, Autonomic Care, and Precision Phenotyping Abstract Background Long COVID, also referred to as post-acute sequelae of SARS-CoV-2 infection (PASC), has emerged as one […]
Long COVID and Dysautonomia: Emerging Insights Into Autonomic Dysfunction, Vagal Pathobiology, Neuroimmune Interactions, and Therapeutic Strategies
John Murphy, M.D., M.P.H., D.P.H. CEO COVID Long-haul Foundation Abstract Background Long COVID, also termed Post-Acute Sequelae of SARS-CoV-2 Infection (PASC), is a complex multisystem disorder characterized by persistent symptoms […]
Long COVID and Autonomic Nervous System Dysfunction
John Murphy, CEO The COVID-19 Long-haul Foundation Abstract Post-acute sequelae of SARS-CoV-2 infection (PASC), commonly termed Long COVID, represents a multisystem disorder characterized by persistent, relapsing, or new-onset symptoms extending […]
Long COVID, Chronic Urticarial Pruritus
Background John Murphy, CEO COV-19 Long-haul Foundation Persistent dermatologic manifestations represent an increasingly recognized component of post-acute sequelae of SARS-CoV-2 infection (PASC), commonly termed Long COVID. Among these manifestations, chronic […]
Long COVID and Dysautonomia
John Murphy, M.D., M.P.H., D.P.H., President, The COVID-19 Lonh-haul Foundation Abstract: Long COVID (post-acute sequelae of SARS-CoV-2 infection, PASC) is increasingly recognized as a heterogeneous syndrome characterized by persistent fatigue, […]
Treatment Landscape in Long COVID Has Expanded Beyond “Supportive Care”
A Mechanism-Driven Reframing of Therapeutic Development in Post–Acute SARS-CoV-2 Disease John Murphy, M.D, M.P.H., D.P.H. President COVID Long-haul Foundation Conceptual Shift and Therapeutic Reclassification ABSTRACT For much of the early […]
COVID-19–Associated Neuropathy of the Feet and Legs: Etiology, Pathophysiology, Clinical Course, and Therapeutic Approaches
Abstract Peripheral neuropathy involving the feet and legs has emerged as one of the most prevalent and disabling neurological sequelae associated with acute and post-acute COVID-19 illness. Although initially overshadowed […]