The COVID-19 Long Haul Foundation

Treatment, Referral & Educational Support for COVID-19 Illnesses & Vaccine Injury

Autonomic dysfunction / Autonomic nerves / Autonomic nervous system disruption / Cardiovascular System / Central autonomic network / CNS / Dysautonomia / Vagus Nerve Posted on:

COVID-19 and Dysautonomia: From Vagal Injury to Systemic Physiological Failure

A narrative review of autonomic dysfunction, vagal disruption, pathophysiology and clinical course in Long COVID Abstract Background: Dysautonomia has emerged as one of the most consequential neurological and cardiovascular manifestations […]

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Autonomic nervous system disruption / Diagnosis / Diagnostic Framework / Diagnostic Test / Diagnostics / Dysautonomia / Endothelial Dysfunction / Endothelium / Epidemiology / Hormonal Dysregulation / Metabolic Dysregulation / Microvascular damage / Microvascular injury / Mitochondria / Mitochondrial dysfunction / Multidisciplinary Care Pathways / Multisystem Disease / Neuroinflammation / Occupational Therapy / Pathobiological / Physical Therapy / Postural Orthostatic Tachycardia (POTS) / Sleep Disturbance / Systems-Based Model / T-cell / Treatments / Viral persistence Posted on:

Multidisciplinary Care Pathways for Long COVID Fatigue:

A Systems-Based Model Integrating Rehabilitation Medicine, Neuroimmunology, Autonomic Care, and Precision Phenotyping Abstract Background Long COVID, also referred to as post-acute sequelae of SARS-CoV-2 infection (PASC), has emerged as one […]

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Autonomic nervous system disruption / COVID-19 / Epigenetic / Long COV / Mitochondrial dysfunction / Pathology / Persistent / Viral persistence Posted on:

Persistent SARS-CoV-2 Reservoirs and the Pathobiology of Long COVID

Etiology, Tissue Persistence, Genomics, Clinical Manifestations, Biomarkers, and Emerging Therapeutic Strategies John Murphy, Chief Executive Officer, The COVID-19 Long-haul Foundation Abstract Background More than four years after the emergence of […]

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Autonomic nerves / Autonomic nervous system disruption / Central autonomic network / CNS / Dysautonomia / Endothelium / Etiology / Gastrointestinal / Immune Modulators / Immune System / Immunopathology / Mitochondrial depletion / Orthostatic intolerance / Outcomes / Pathology / Pathophysiology / Postural Orthostatic Tachycardia (POTS) / Sleep Disturbance / Tachycardia / Temperature / Treatments / Vagus Nerve Posted on:

Long COVID and Dysautonomia: Emerging Insights Into Autonomic Dysfunction, Vagal Pathobiology, Neuroimmune Interactions, and Therapeutic Strategies

John Murphy, M.D., M.P.H., D.P.H. CEO COVID Long-haul Foundation Abstract Background Long COVID, also termed Post-Acute Sequelae of SARS-CoV-2 Infection (PASC), is a complex multisystem disorder characterized by persistent symptoms […]

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Autonomic nervous system disruption / Central autonomic network / CNS / Dysautonomia / Enteric nervous system / Parasympathetic nervous system / Sympathetic nervous system Posted on:

Long COVID and Autonomic Nervous System Dysfunction

John Murphy, CEO The COVID-19 Long-haul Foundation Abstract Post-acute sequelae of SARS-CoV-2 infection (PASC), commonly termed Long COVID, represents a multisystem disorder characterized by persistent, relapsing, or new-onset symptoms extending […]

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Autonomic nervous system disruption / Balance / CNS / Finger / Foot / Gait / Hand / Microvascular injury / Nerve Cell Injury / Nerve damage / Numbness / PASC / Peripheral nerve / Proprioception / Quality of Life / Sensory nerves / Temperature Posted on:

Peripheral Sensory Dysfunction in Long COVID: Etiology, Genomics, Pathophysiology, Clinical Manifestations, Diagnostic Approaches, Disease Progression, and Long-Term Outcomes

John Murphy, MD., M.P.H., D.P.H., CEO, COVID-19 long-haul Foundation Abstract Long COVID, also known as Post-Acute Sequelae of SARS-CoV-2 Infection (PASC), has emerged as one of the most significant chronic […]

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Autonomic nervous system disruption / Clinical Trials / Cognitive deficit / Cognitive Deficits / Endothelium / Immune dysregulation / Immunity / Metabonomics / Neurologic Effects / Neuropathy / Recover / Treatments Posted on:

NIH RECOVER Clinical Trials and the First Emergence of Interventional Results in Long COVID Research: A Translational Turning Point

A Scholarly Review for Scientific American (Submission-Style Manuscript) John Murphy, M.D., M.P.H., D.P.H., President, COVID-19 Long-Haul Foundation Abstract The NIH RECOVER Initiative represents the largest coordinated research program investigating post–acute […]

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Autonomic nervous system disruption / Brain / Cognitive deficit / Cytokine Storm / Endothelium / Fatigue / Hyperinflammation / Inflammasome / Inflammation / Inflammation / Microvascular damage / Mitochondria / Mitochondrial dysfunction / Mitochondrial Effects / Neuropathy Posted on:

Persistent Viral Reservoirs and Immune Dysregulation in Long COVID

John Murphy, M.D., M.P.H., D.P.H., President Covid-19 Long-haul Foundation The Central Discovery Reshaping Post-Acute Sequelae Research Abstract Long COVID (post-acute sequelae of SARS-CoV-2 infection, PASC) has emerged as a multisystem […]

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Autonomic nervous system disruption / Chronic Fatigue / Fatigue / Immune dysregulation / Long-haul Disease / Malaise-Fatigue / ME/CFS / Microvascular damage / Mitochondrial dysfunction / Viral persistence Posted on:

The Lingering Pandemic: Mapping the Arc of Long COVID and the Search for Recovery

By John Murphy, The COVID 19 Long-haul Foundation Introduction: A Pandemic That Didn’t End When the world first confronted SARS-CoV-2 in early 2020, the prevailing narrative was one of acute […]

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