Category: Pneumonia

How does coronavirus kill? Clinicians trace a ferocious rampage through the body, from brain to toes

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Authors: By Meredith Wadman, Jennifer Couzin-Frankel, Jocelyn Kaiser, Catherine MatacicApr. 17, 2020 , 6:45 PM On rounds in a 20-bed intensive care unit one recent day, physician Joshua Denson assessed two patients with seizures, many with respiratory failure and others whose kidneys were on a dangerous downhill slide. Days earlier, his rounds had been interrupted as his team tried, […]

Pathological findings in organs and tissues of patients with COVID-19: A systematic review

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Authors: Sasha Peiris 1 2, Hector Mesa 3, Agnes Aysola 4, Juan Manivel 5, Joao Toledo 1 2, Marcio Borges-Sa 6, Sylvain Aldighieri 1 2, Ludovic Reveiz 2 7 Abstract Background: Coronavirus disease (COVID-19) is the pandemic caused by SARS-CoV-2 that has caused more than 2.2 million deaths worldwide. We summarize the reported pathologic findings on biopsy and autopsy in patients with severe/fatal COVID-19 and documented the presence and/or effect of SARS-CoV-2 in all organs. […]

Covid-19 Vaccine Analysis: The most common adverse events reported so far

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Authors: DATED: AUGUST 6, 2021 BY SHARYL ATTKISSON  As of July 19, 2021 there were 419,513 adverse event reports associated with Covid-19 vaccination in the U.S., with a total of 1,814,326 symptoms reported. That’s according to the federal Vaccine Adverse Event Reporting System (VAERS) database. Report an adverse event after vaccination online here. Each symptom reported does […]

Characteristics of SARS-CoV-2 and COVID-19

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Authors: Ben Hu, Hua Guo, Peng Zhou & Zheng-Li Shi  Nature Reviews Microbiology volume 19, pages141–154 (2021) Abstract Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a highly transmissible and pathogenic coronavirus that emerged in late 2019 and has caused a pandemic of acute respiratory disease, named ‘coronavirus disease 2019’ (COVID-19), which threatens human health and public safety. In this Review, we […]

Overweight/obesity as the potentially most important lifestyle factor associated with signs of pneumonia in COVID-19

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Authors: Vanessa Sacco ,Barbara Rauch ,Christina Gar,Stefanie Haschka,Anne L. Potzel,Stefanie Kern-Matschilles,Friederike Banning,Irina Benz,Mandy Meisel,Jochen Seissler,Andreas Lechner  Published: November 18, 2020 Abstract Objective The occurrence of pneumonia separates severe cases of COVID-19 from the majority of cases with mild disease. However, the factors determining whether or not pneumonia develops remain to be fully uncovered. We therefore explored the […]

COVID-19-Associated Bronchiectasis and Its Impact on Prognosis

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Authors: Aasir M. Suliman, Bassel W. Bitar, Amer A. Farooqi, Anam M. Elarabi, Mohamed R. Aboukamar, Ahmed S. Abdulhadi Abstract Coronavirus disease 2019 (COVID-19), which initially emerged in Wuhan, China, has rapidly swept around the world, causing grave morbidity and mortality. It manifests with several symptoms, on a spectrum from asymptomatic to severe illness and death. Many typical imaging features […]

Comorbidity and its Impact on Patients with COVID-19

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Authors: Adekunle Sanyaolu 1, Chuku Okorie 2, Aleksandra Marinkovic 3, Risha Patidar 3, Kokab Younis 4, Priyank Desai 5, Zaheeda Hosein 6, Inderbir Padda 7, Jasmine Mangat 6, Mohsin Altaf 8 Abstract A novel human coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), was identified in Wuhan, China, in December 2019. Since then, the virus has made its way across the globe to affect over 180 countries. SARS-CoV-2 has infected humans in all age […]

Virology, transmission, and pathogenesis of SARS-CoV-2

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Authors: Muge Cevik, clinical lecturer1 2,  Krutika Kuppalli, assistant professor3,  Jason Kindrachuk, assistant professor of virology4,  Malik Peiris, professor of virology5 What you need to know SARS-CoV-2 is genetically similar to SARS-CoV-1, but characteristics of SARS-CoV-2—eg, structural differences in its surface proteins and viral load kinetics—may help explain its enhanced rate of transmission In the respiratory […]

Severe covid-19 pneumonia: pathogenesis and clinical management

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Authors: Amy H Attaway, assistant professor of medicine, associate director, COPD center1,  Rachel G Scheraga, assistant professor of medicine1 2,  Adarsh Bhimraj, head, section of neurological infections; staff, infectious diseases1,  Michelle Biehl, associate staff, pulmonary and critical care medicine; director, post ICU recovery clinic1,  Umur Hatipoğlu, associate professor of medicine; director, respiratory therapy; director, COPD center1 […]

Platelets Promote Thromboinflammation in SARS-CoV-2 Pneumonia

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Authors: Francesco Taus, Gianluca Salvagno, Stefania Canè, Cristiano Fava, Fulvia Mazzaferri, Elena Carrara, Varvara Petrova, Roza Maria Barouni, Francesco Dima, Andrea Dalbeni, Simone Romano, Abstract Objective: Pulmonary thrombosis is observed in severe acute respiratory syndrome coronavirus 2 pneumonia. Aim was to investigate whether subpopulations of platelets were programmed to procoagulant and inflammatory activities in coronavirus disease 2019 (COVID-19) patients with pneumonia, without comorbidities predisposing to […]