Category: Cognitive deficit

Cognition and Memory after Covid-19 in a Large Community Sample

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Authors.Adam Hampshire, Ph.D., Adriana Azor, Ph.D., et. al. 2024,N Engl J Med 2024; 390:806-818 DOI: 10.1056/NEJMoa2311330 Abstract BACKGROUND Cognitive symptoms after coronavirus disease 2019 (Covid-19), the disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), are well-recognized. Whether objectively measurable cognitive deficits exist and how long they persist are unclear. METHODS We invited 800,000 adults in […]

COVID-19 Lockdowns Linked To Memory, Cognitive Decline: UK Study

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NOV, 2023 – Authored by Caden Pearson via The Epoch Times  The stringent lockdown measures implemented worldwide during the COVID-19 pandemic have been found to significantly affect the working memory and cognitive function of older individuals, raising concerns about an elevated risk of dementia, according to a comprehensive UK study. Researchers in the UK delved into neuropsychology […]

Evaluation of Post–COVID-19 Cognitive Dysfunction: Recommendations for Researchers

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Jaqueline H. Becker, PhD1; Tracy D. Vannorsdall, PhD2; Sara L. Weisenbach, PhD3, JAMA Psychiatry. 2023;80(11):1085-1086. doi:10.1001/jamapsychiatry.2023.2820 SARS-CoV-2 infection is associated with increased rates of postillness cognitive dysfunction, colloquially referred to as “brain fog,”1 that may portend significant consequences for patient functioning and quality of life. Post–COVID-19 cognitive dysfunction is 1 of approximately 200 symptoms of post–COVID-19 condition (PCC), defined by the World Health Organization as […]

SARS-CoV-2 is associated with changes in brain structure in UK Biobank

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Gwenaëlle Douaud, Soojin Lee, Fidel Alfaro-Almagro, Christoph Arthofer, Chaoyue Wang, et. al. Nature volume 604, pages697–707 (2022)Cite this article Abstract There is strong evidence of brain-related abnormalities in COVID-191,2,3,4,5,6,7,8,9,10,11,12,13. However, it remains unknown whether the impact of SARS-CoV-2 infection can be detected in milder cases, and whether this can reveal possible mechanisms contributing to brain pathology. Here we investigated brain changes in 785 […]

Long COVID: Antibodies in cerebrospinal fluid linked with brain fog

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Deep Shukla, 2022 Medical News Today Coronavirus data Brain fog, or cognitive dysfunction, is one of the most common symptoms that health professionals observe in individuals with long COVID, or post-acute COVID-19. A recent study by researchers at the University of California, San Francisco (UCSF) suggests a link between the presence of persistent cognitive symptoms several months after a SARS-CoV-2 […]

Potential molecular mechanisms of chronic fatigue in long haul COVID and other viral diseases

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Carl Gunnar Gottschalk, Daniel Peterson, Jan Armstrong, Konstance Knox & Avik Roy  Infectious Agents and Cancer volume 18, Article number: 7 (2023) Cite this article, A Correction to this article was published on 24 April 2023 Abstract Historically, COVID-19 emerges as one of the most devastating diseases of humankind, which creates an unmanageable health crisis worldwide. Until now, this disease costs millions of lives and continues to paralyze […]

Treatment of Long COVID symptoms with triple anticoagulant therapy

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Gert J Laubscher, M Asad Khan, Chantelle Venter, Jan H Pretorius, and 2 more, This is a preprint; it has not been peer reviewed by a journal. https://doi.org/10.21203/rs.3.rs-2697680/v1 Research Square Abstract Background: Fibrin(ogen) amyloid microclots and platelet hyperactivation are key pathological findings in patients with acute COVID-19 infection and also in those with Long COVID/Post-Acute Sequelae […]

What is the long-term cognitive impact of COVID-19, and what are its predictors?

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Dr. Sanchari Sinha Dutta, Ph.D. Jan 9 2023 Reviewed by Danielle Ellis, B.Sc. Medical Life Sciences Neuropsychology Background Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative pathogen of COVID-19, has caused massive damage to the healthcare and economic sectors worldwide. Although the virus causes asymptomatic or mildly symptomatic infection in most affected individuals, long-term clinical […]

Alteration of the blood-brain barrier by COVID-19 and its implication in the permeation of drugs into the brain

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Héctor Hernández-Parra1,2 Octavio Daniel Reyes-Hernández3 Gabriela Figueroa-González4 Manuel González-Del Carmen5 Maykel González-Torres6 Sheila I. Peña-Corona2 Benjamín Florán7 Hernán Cortés8* Gerardo Leyva-Gómez2* https://pubmed.ncbi.nlm.nih.gov/36998270/ Diverse neurological symptoms have been reported in patients with SARS-CoV-2 disease (COVID-19), including stroke, ataxia, meningitis, encephalitis, and cognitive impairment. These alterations can cause serious sequelae or death and are associated with the entry of SARS-CoV-2 into the Central Nervous System […]

Brainstem volume changes in myalgic encephalomyelitis/chronic fatigue syndrome and long COVID patients

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Kiran Thapaliya, 1 , 2 , * Sonya Marshall-Gradisnik, 1 Markus Barth, 2 , 3 Natalie Eaton-Fitch, 1 and Leighton Barnden 1 Front Neurosci. 2023; 17: 1125208. Published online 2023 Mar 2. doi: 10.3389/fnins.2023.1125208 PMCID: PMC10017877 PMID: 36937672 Abstract Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and long COVID patients have overlapping neurological, autonomic, pain, and post-exertional symptoms. We compared volumes of brainstem regions for 10 ME/CFS (CCC or ICC criteria), 8 long COVID (WHO […]