Category: Micro vessels

SARS-CoV-2 is associated with changes in brain structure in UK Biobank

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Gwenaëlle Douaud, Soojin Lee, Fidel Alfaro-Almagro, Christoph Arthofer, Chaoyue Wang, et. al. Nature volume 604, pages697–707 (2022)Cite this article Abstract There is strong evidence of brain-related abnormalities in COVID-191,2,3,4,5,6,7,8,9,10,11,12,13. However, it remains unknown whether the impact of SARS-CoV-2 infection can be detected in milder cases, and whether this can reveal possible mechanisms contributing to brain pathology. Here we investigated brain changes in 785 […]

Unraveling long COVID: Here’s what scientists who study the illness want to find out

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September 9, 2023, By Will Stone NPR Newsletter Researchers looking for root causes of long COVID work in the autopsy suite inside the Clinical Center at the National Institute of Health in Bethesda, Maryland. Valerie Plesch/Bloomberg via Getty Images For people suffering from long COVID’s often disabling symptoms, including intense fatigue, breathing troubles, cognitive issues and heart […]

Microvascular Injury in the Brains of Patients with Covid-19

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February 4, 2021 N Engl J Med 2021; 384:481-483 DOI: 10.1056/NEJMc2033369 304 Citing Articles TO THE EDITOR: We conducted postmortem high-resolution magnetic resonance imaging (magnetic resonance microscopy) of the brains of patients with coronavirus disease 2019 (Covid-19) (median age, 50 years) and histopathological examination that focused on microvascular changes in the olfactory bulb and brain stem. […]

Intestinal Damage in COVID-19: SARS-CoV-2 Infection and Intestinal Thrombosis

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Authors: Xiaoming Wu1, Haijiao Jing1, Chengyue Wang1, Yufeng Wang1, Nan Zuo1, Tao Jiang2*, Valerie A. Novakovic3 and Jialan Shi1,3,4* Front. Microbiol., 22 March 2022 | https://doi.org/10.3389/fmicb.2022.860931 The intestinal tract, with high expression of angiotensin-converting enzyme 2 (ACE2), is a major site of extrapulmonary infection in COVID-19. During pulmonary infection, the virus enters the bloodstream forming viremia, which infects and damages extrapulmonary organs. Uncontrolled viral […]

Review of Mesenteric Ischemia in COVID-19 Patients

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Authors: Amit Gupta, Oshin Sharma, Kandhala Srikanth, Rahul Mishra, Amoli Tandon & Deepak Rajput  Indian Journal of Surgery (2022) Published: 11 March 2022 Abstract The new coronavirus (COVID-19) infection, first detected in Wuhan, China in 2019 has become a pandemic that has spread to nearly every country in the world. Through October 11, 2021, more than 23 billion confirmed cases and 4.8 million […]

COVID-19 – A vascular disease

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Authors: Hasan K. Siddiqi,a,bPeter Libby,a,⁎ and Paul M Ridkera,b Abstract Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) leads to multi-system dysfunction with emerging evidence suggesting that SARS-CoV-2-mediated endothelial injury is an important effector of the virus. Potential therapies that address vascular system dysfunction and its sequelae may have an important role in treating SARS-CoV-2 infection and its […]