SARS-CoV-2 infection modifies the transcriptome of the megakaryocytes in the bone marrow


Isabelle Allaeys, Guillaume Lemaire, Mickaël Leclercq, et. al. Blood Adv (2024) 8 (11): 2777–2789. In a mouse model of SARS-CoV-2 infection, cytokines in the bone marrow are different from those in…[...]

Bone Marrow Suppression Secondary to the COVID-19 Booster Vaccine: A Case Report


TAuthors: oral Shastri 1, Navkiran Randhawa 2, Ragia Aly 3, Masood Ghouse 3 PMID: 35210894PMCID: PMC8863340DOI: 10.2147/JBM.S350290 J Blood Med.  2022; 13: 69–74.Published online 2022 Feb 18. doi: 10.2147/JBM.S350290 Abstract As of September 2021, SARS-CoV-2 booster shots became widely available in the…[...]

Severe aplastic anemia after COVID-19 mRNA vaccination: Causality or coincidence?


Authors: Shotaro Tabata 1, Hiroki Hosoi 2, Shogo Murata 1, Satomi Takeda 1, Toshiki Mushino 1, Takashi Sonoki 1PMID: 34920343 PMCID: PMC8668346I: 10.1016/j.jaut.2021.102782 J Autoimmun. 2022 Jan; 126: 102782.Published online 2021 Dec 14. doi: 10.1016/j.jaut.2021.102782 Abstract The development of various autoimmune diseases has been reported after COVID-19…[...]

Bone Marrow Suppression Secondary to the COVID-19 Booster Vaccine: A Case Report


Authors: Toral Shastri 1, Navkiran Randhawa 2, Ragia Aly 3, Masood Ghouse 3 PMID: 35210894 PMCID: PMC8863340DOI: 10.2147/JBM.S350290 Abstract As of September 2021, SARS-CoV-2 booster shots became widely available in the US to ensure continued protection against the virus. A…[...]

SARS-CoV-2 infection induces long-lived bone marrow plasma cells in humans


Authors: Jackson S. Turner, Wooseob Kim, Elizaveta Kalaidina, Charles W. Goss, Adriana M. Rauseo, Aaron J. Schmitz, Lena Hansen, Alem Haile, Michael K. Klebert, Iskra Pusic, Jane A. O’Halloran, Rachel M. Presti & Ali H. Ellebedy  Nature volume 595, pages421–425 (2021) Abstract Long-lived bone marrow plasma…[...]

Trained Innate Immunity, Epigenetics, and Covid-19


Authors: Alberto Mantovani, M.D., and Mihai G. Netea, M.D. Innate immunity is mediated by different cell types and cell-associated or fluid-phase pattern-recognition molecules and plays a key role in tissue repair…[...]

Good news: Mild COVID-19 induces lasting antibody protection


People who have had mild illness develop antibody-producing cells that can last lifetime Authors: by Tamara Bhandari•May 24, 2021 Months after recovering from mild cases of COVID-19, people still have immune…[...]