Authors: Geoffrey D Wool 1, Jonathan L Miller 2 Abstract Coronavirus disease 2019 (COVID-19) causes a spectrum of disease; some patients develop a severe proinflammatory state which can be associated with a unique […]
Insights into How SARS-CoV-2 Causes Brain Pathology
Authors: Anthony L. Komaroff, MD, reviewing Yang AC et al. Nature 2021 Jul Marshall M. Nature 2021 Jul In deceased COVID-19 patients, gene expression in the choroid plexus was altered. People infected with SARS-CoV-2 can […]
SARS-CoV-2 Infects the Brain Choroid Plexus and Disrupts the Blood-CSF Barrier in Human Brain Organoids
Authors: Laura Pellegrini 1, Anna Albecka 1, Donna L Mallery 1, Max J Kellner 1, David Paul 1, Andrew P Carter 1, Leo C James 1, Madeline A Lancaster 2 Abstract Coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) […]
NIH study uncovers blood vessel damage and inflammation in COVID-19 patients’ brains but no infection
Authors: Christopher G. Thomas, 301-496-5751, nindspressteam@ninds.nih.gov Results from a study of 19 deceased patients suggests brain damage is a byproduct of a patient’s illness. In an in-depth study of how COVID-19 […]
COVID and the brain: researchers zero in on how damage occurs
Authors: Michael Marshall Growing evidence suggests that the coronavirus causes ‘brain fog’ and other neurological symptoms through multiple mechanisms. How COVID-19 damages the brain is becoming clearer. New evidence suggests […]
The complement system in COVID-19: friend and foe?
Authors: Anuja Java,1 Anthony J. Apicelli,2 M. Kathryn Liszewski,3 Ariella Coler-Reilly,3 John P. Atkinson,3 Alfred H.J. Kim,3 and Hrishikesh S. Kulkarni4 Coronavirus disease 2019 (COVID-19), the disease caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has resulted […]
Direct activation of the alternative complement pathway by SARS-CoV-2 spike proteins is blocked by factor D inhibition
Authors: Jia Yu, Xuan Yuan, Hang Chen, Shruti Chaturvedi, Evan M. Braunstein, Robert A. Brodsky Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a highly contagious respiratory virus that can lead to venous/arterial thrombosis, stroke, […]
Hypercoagulability in COVID-19: A review of the potential mechanisms underlying clotting disorders
Authors: Walid Alam Severe acute respiratory syndrome coronavirus-2 has emerged as a new viral pandemic, causing Coronavirus disease 2019 (COVID-19) leading to a wide array of symptoms ranging from asymptomatic […]
SARS-CoV-2 spike protein-mediated cell signaling in lung vascular cells
Authors: Yuichiro J. Suzuki,a,⁎ Sofia I. Nikolaienko,b Vyacheslav A. Dibrova,b Yulia V. Dibrova,b Volodymyr M. Vasylyk,c Mykhailo Y. Novikov,d Nataliia V. Shults,a and Sergiy G. Gychkab Currently, the world is suffering from the pandemic of coronavirus disease 2019 […]
Dr. Charles Hoffe issues Vaccine warning… Deep dive on endothelial damage to blood vessels…
Author: Dr. Charles Hoffe in a Coronavirus, that spike protein becomes part of the viral capsule. In other words, the cell wall around the virus, called the viral capsule. But […]