Deep Vein Thrombosis – The COVID-19 Long Haul Foundation

Diagnosis of venous thromboembolic diseases in people with covid-19: summary of updated NICE guidance

November 4, 2023 | John Murphy | Leave a Comment

BMJ 2023; 383 doi: https://doi.org/10.1136/bmj.p2204 (Published 12 October 2023)Cite this as: BMJ 2023;383:p2204, Sarah Boyce, senior technical analyst1, Emma McFarlane, Susan Harrison, Terry McCormack What you need to know In venous thromboembolism, a blood clot usually forms in the deep veins of the legs or pelvis. This is known as deep vein thrombosis, and the blood clot can dislodge from these sites, […]

Auditory Disturbances and SARS-CoV-2 Infection: Brain Inflammation or Cochlear Affection? Systematic Review and Discussion of Potential Pathogenesis

November 19, 2022 | John Murphy | Leave a Comment

Pietro De Luca1, Alfonso Scarpa1, Massimo Ralli2, Domenico Tassone3, Matteo Simone3, Luca De Campora3, Claudia Cassandro4† and Arianna Di Stadio Frontiers in Medicine Patients affected by COVID-19 present a series of different symptoms; despite some of these are common, other less likely appear. Auditory symptoms seem to be less frequent, maybe because rarer or, alternatively, because they are underestimated during the clinical investigation. […]

Extensive thrombosis after COVID-19 vaccine: cause or coincidence

April 14, 2022 | John Murphy | Leave a Comment

Authors: Luís Lourenço Graça ,1 Maria João Amaral ,2 Marco Serôdio,3 Beatriz Costa2 SUMMARYA 62-year-old Caucasian female patient presented with abdominal pain, vomiting and fever 1 day after administration of COVID-19 vaccine. Bloodwork revealed anaemia and thrombocytosis. Abdominal CT angiography showed a mural thrombus at the emergence of the coeliac trunk, hepatic and splenic arteries, […]

Intestinal Damage in COVID-19: SARS-CoV-2 Infection and Intestinal Thrombosis

April 13, 2022 | John Murphy | Leave a Comment

Authors: Xiaoming Wu1, Haijiao Jing1, Chengyue Wang1, Yufeng Wang1, Nan Zuo1, Tao Jiang2*, Valerie A. Novakovic3 and Jialan Shi1,3,4* Front. Microbiol., 22 March 2022 | https://doi.org/10.3389/fmicb.2022.860931 The intestinal tract, with high expression of angiotensin-converting enzyme 2 (ACE2), is a major site of extrapulmonary infection in COVID-19. During pulmonary infection, the virus enters the bloodstream forming viremia, which infects and damages extrapulmonary organs. Uncontrolled viral […]

Review of Mesenteric Ischemia in COVID-19 Patients

April 13, 2022 | John Murphy | Leave a Comment

Authors: Amit Gupta, Oshin Sharma, Kandhala Srikanth, Rahul Mishra, Amoli Tandon & Deepak Rajput Indian Journal of Surgery (2022) Published: 11 March 2022 Abstract The new coronavirus (COVID-19) infection, first detected in Wuhan, China in 2019 has become a pandemic that has spread to nearly every country in the world. Through October 11, 2021, more than 23 billion confirmed cases and 4.8 million […]

COVID‐19‐induced endotheliitis: emerging evidence and possible therapeutic strategies

February 3, 2022 | John Murphy | Leave a Comment

Authors: Eleonora Calabretta, 1 , 12 Jose M. Moraleda, 2 Massimo Iacobelli, 3 Ruben Jara, 4 Israel Vlodavsky, 5 Peter O’Gorman, 6 Antonio Pagliuca, 7 Clifton Mo, 8 Rebecca M. Baron, 9 Alessio Aghemo, 10 , 12 Robert Soiffer, 8 Jawed Fareed, 11 Carmelo Carlo‐Stella, 1 , 12 , * and Paul Richardson 8 , * Br J Haematol. 2021 Apr; 193(1): 43–51.Published online 2021 Feb 4. doi: 10.1111/bjh.17240 PMCID: PMC8014053PMID: 33538335 Introduction The coronavirus disease 2019 (COVID‐19) pandemic, a viral illness caused by the severe acute respiratory syndrome coronavirus‐2 […]

Review of COVID-19, part 1: Abdominal manifestations in adults and multisystem inflammatory syndrome in children

January 6, 2022 | John Murphy | Leave a Comment

Authors: Devaraju Kanmaniraja,a,⁎ Jessica Kurian,a Justin Holder,a Molly Somberg Gunther,a Victoria Chernyak,b Kevin Hsu,a Jimmy Lee,a Andrew Mcclelland,a Shira E. Slasky,a Jenna Le,a and Zina J. Riccia Abstract The coronavirus disease 2019 (COVID -19) pandemic caused by the novel severe acute respiratory syndrome coronavirus (SARS-CoV-2) has affected almost every country in the world, resulting in severe morbidity, mortality and economic hardship, and altering the landscape of […]

Coronavirus (Covid-19)

August 20, 2021 | John Murphy | Leave a Comment

A collection of articles and other resources on the Coronavirus (Covid-19) outbreak, including clinical reports, management guidelines, and commentary. CORONAVIRUS (COVID-19) VACCINE RESOURCES VACCINE FAQ https://www.nejm.org/coronavirus All Journal content related to the Covid-19 pandemic is freely available. ORIGINAL ARTICLEConvalescent Plasma for High-Risk Covid-19F.K. Korley and OthersPatients who were seen in emergency departments within 7 days after the onset of Covid-19 symptoms […]

Recent Randomized Trials of Antithrombotic Therapy for Patients With COVID-19

August 19, 2021 | John Murphy | Leave a Comment

Authors: JACC State-of-the-Art ReviewAzita H. Talasaz, PharmD,a,bParham Sadeghipour, MD,cHessam Kakavand, PharmD,a,bMaryam Aghakouchakzadeh, PharmD,aElaheh Kordzadeh-Kermani, PharmD,aBenjamin W. Van Tassell, PharmD,d,eAzin Gheymati, PharmD,aHamid Ariannejad, MD,bSeyed Hossein Hosseini, PharmD,aSepehr Jamalkhani,cMichelle Sholzberg, MDCM, MSc,f,gManuel Monreal, MD, PhD,hDavid Jimenez, MD, PhD,iGregory Piazza, MD, MS,jSahil A. Parikh, MD,k,lAjay J. Kirtane, MD, SM,k,lJohn W. Eikelboom, MBBS,mJean M. Connors, MD,nBeverley J. Hunt, MD,oStavros V. […]

COVID-19 vaccines and thrombosis with thrombocytopenia syndrome

August 19, 2021 | John Murphy | Leave a Comment

Authors: Chih-Cheng Lai 1, Wen-Chien Ko 2, Chih-Jung Chen 3, Po-Yen Chen 4, Yhu-Chering Huang 3, Ping-Ing Lee 5, Po-Ren Hsueh 6 7 Abstract Introduction: To combat COVID-19, scientists all over the world have expedited the process of vaccine development. Although interim analyses of clinical trials have demonstrated the efficacy and safety of COVID-19 vaccines, a serious but rare adverse event, thrombosis with thrombocytopenia syndrome (TTS), has been reported following […]