Six years after SARS-CoV-2 emerged, researchers are no longer asking whether patients are sick. They are trying to understand why the same infection can leave one person with debilitating fatigue, […]
Mitochondrial and Metabolic Dysfunction in Long COVID: A Bioenergetic Model of Fatigue, Post-Exertional Malaise, and Multisystem Disease
Etiology, pathology, genomics, physiology, and clinical course Abstract Long COVID, or post-acute sequelae of SARS-CoV-2 infection (PASC), is a heterogeneous multisystem disorder in which fatigue, post-exertional malaise, cognitive dysfunction, autonomic […]
Recognition of Long COVID as a Heterogeneous Post-Infectious Syndrome
Toward a Multisystem Endotype Framework for Post–Acute SARS-CoV-2 Disease John Murphy, M.D., M.P.H., D.P.H. President Covid-19 Long-haul Foundation Abstract Long COVID (post–acute sequelae of SARS-CoV-2 infection, PASC) has emerged as […]