Authors: Jackson S. Turner, Wooseob Kim, Elizaveta Kalaidina, Charles W. Goss, Adriana M. Rauseo, Aaron J. Schmitz, Lena Hansen, Alem Haile, Michael K. Klebert, Iskra Pusic, Jane A. O’Halloran, Rachel M. Presti & Ali H. Ellebedy Nature volume 595, pages421–425 (2021) Abstract Long-lived bone marrow plasma […]
Adaptive immunity to SARS-CoV-2 and COVID-19
Authors: Alessandro Sette1,2 and Shane Crotty1,2,* 1Center for Infectious Disease and Vaccine Research, La Jolla Institute for Immunology (LJI), La Jolla, CA 92037, USA2Department of Medicine, Division of Infectious Diseases […]
Pre-existing immunity to SARS-CoV-2: the knowns and unknowns
Authors: Alessandro Sette 1 2, Shane Crotty 3 4 Abstract T cell reactivity against SARS-CoV-2 was observed in unexposed people; however, the source and clinical relevance of the reactivity remains unknown. It is speculated that […]
A long-term perspective on immunity to COVID
Determining the duration of protective immunity to infection by SARS-CoV-2 is crucial for understanding and predicting the course of the COVID-19 pandemic. Clinical studies now indicate that immunity will be […]
COVID-19 survivors may possess wide-ranging resistance to the disease
Authors: Rajee Suri rajee.suri@emory.edu Recovered COVID-19 patients retain broad and effective longer-term immunity to the disease, suggests a recent Emory University study, which is the most comprehensive of its kind […]
Adaptive immune responses to SARS-CoV-2 infection in severe versus mild individuals
Authors: Fan Zhang, Rui Gan, Ziqi Zhen, Xiaoli Hu, Xiang Li, Fengxia Zhou, Ying Liu, Chuangeng Chen, Shuangyu Xie, Bailing Zhang, Xiaoke Wu & Zhiwei Huang Signal Transduction and Targeted Therapy volume 5, Article number: 156 (2020) Abstract The global Coronavirus disease 2019 (COVID-19) pandemic caused by SARS-CoV-2 […]
Adaptive immunity to SARS-CoV-2 and COVID-19
Authors: Alessandro Sette1,2 and Shane Crotty1,2,∗ Abstract The adaptive immune system is important for control of most viral infections. The three fundamental components of the adaptive immune system are B cells (the […]
Adaptive immunity to SARS-CoV-2 and COVID-19
Authors: Alessandro Sette 1, Shane Crotty 2 Abstract The adaptive immune system is important for control of most viral infections. The three fundamental components of the adaptive immune system are B cells (the […]
Walking down the memory lane with SARS-CoV-2 B cells
Authors: Natalia T Freund, Motti Gerlic, Ben A Croker The end of the coronavirus disease 2019 (COVID-19) pandemic is in sight. We have scientists to thank for that. However, while years of […]
Not just antibodies: B cells and T cells mediate immunity to COVID-19
Authors: Rebecca J. Cox & Karl A. Brokstad Nature Reviews Immunology volume 20, pages581–582 (2020) Recent reports that antibodies to SARS-CoV-2 are not maintained in the serum following recovery from the virus have caused alarm. However, […]