Unlocking life-threatening COVID-19 through two types of inborn errors of type I IFNs


Jean-Laurent Casanova1,2,3,4,5 and Mark S. Anderson6,7, Published February 1, 2023 - More infoView PDF Abstract Since 2003, rare inborn errors of human type I IFN immunity have been discovered, each underlying a few severe…[...]

No evidence of durable trained immunity after two doses of adenovirus-vectored or mRNA COVID-19 vaccines


Natalie E. Stevens,1,2 Feargal J. Ryan,1,2 Nicole L. Messina,3,4 Stephen J. Blake,1,2 Todd S. Norton,1 Susie Germano,3 Jane James,1 Georgina L. Eden,1 Yee C. Tee,1,2 Miriam A. Lynn,1,2 Rochelle Botten,1 Simone E. Barry,5 Nigel Curtis,3,4 and David J. Lynn1,2 Published July 20, 2023 - September…[...]

Immunological dysfunction persists for 8 months following initial mild-to-moderate SARS-CoV-2 infection


Authors: Chansavath Phetsouphanh, David R. Darley, Daniel B. Wilson, Annett Howe, C. Mee Ling Munier, Sheila K. Patel, Jennifer A. Juno, Louise M. Burrell, Stephen J. Kent, Gregory J. Dore, Anthony D. Kelleher & Gail V. Matthews  Nature Immunology volume 23, pages210–216 (2022) June 30,…[...]

Mount Sinai researchers develop a rapid test to measure immunity to COVID-19


New blood assay provides critical information for revaccination strategies in vulnerable individuals Peer-Reviewed Publication THE MOUNT SINAI HOSPITAL / MOUNT SINAI SCHOOL OF MEDICINE Mount Sinai researchers have developed a…[...]

Why COVID-19 Is Here to Stay, and Why You Shouldn’t Worry About It


Authors: August 17, 2021 by Philippe Lemoine As many countries are going through another wave of infections, including some where the vast majority of the population has been vaccinated, many are starting…[...]

Evolution of NETosis markers and DAMPs have prognostic value in critically ill COVID-19 patients


Authors: Joram Huckriede, Sara Bülow Anderberg, Albert Morales, Femke de Vries, Michael Hultström, Anders Bergqvist, José T. Ortiz-Pérez, Jan Willem Sels, Kanin Wichapong, Miklos Lipcsey, Marcel van de Poll, Anders Larsson, Tomas Luther, Chris Reutelingsperger, Pablo Garcia de Frutos, Robert Frithiof & Gerry A. F. Nicolaes  Scientific…[...]