John Murphy, CEO COVID-19 Long-haul foundation I. Introduction: The Immune System Under Siege The immune system is a dynamic, multilayered defense network composed of innate and adaptive components, designed to […]
Persistent SARS-CoV-2 Spike Protein: Genomic Modulation, Immune Dysregulation, and Impaired Antibody Maturation
Author: John Murphy, CEO COVID 19 Long-haul Foundation Abstract The SARS-CoV-2 spike glycoprotein, central to viral entry and the target of mRNA vaccine platforms, has emerged as a persistent antigen […]
COVID-19 and immune dysregulation: Genomic pathways, clinical manifestations, and therapeutic strategies
John Murphy, CEO & President, COVID-19 Long-haul Foundation Abstract SARS-CoV-2 provokes a uniquely heterogeneous and dynamic immune response that ranges from efficient viral control to fulminant hyperinflammation and prolonged immune […]
Long Covid: Hormone Imbalances and/or Rather Complex Immune Dysregulations?
Christian A Koch, Journal of the Endocrine Society, Volume 8, Issue 5, May 2024, bvae043, https://doi.org/10.1210/jendso/bvae043 Commentary Approximately 5% of all individuals infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) […]
Immunological and Antigenic Signatures Associated with Chronic Illnesses after COVID-19 Vaccination
Bornali Bhattacharjee, Peiwen Lu, Valter Silva Monteiro, et. al. doi: https://doi.org/10.1101/2025.02.18.25322379 Yale Study Reveals Shocking Truth: Spike Protein Lingers – and Grows SUMMARY COVID-19 vaccines have prevented millions of COVID-19 deaths. Yet, a small fraction of the […]
Statistical Analysis of Multiple Vaccine Effectiveness Against COVID-19 Variants
Abstract The study aims to evaluate the association between multiple COVID-19 vaccine doses and daily confirmed cases, incorporating immune response delays to better understand vaccination efficacy. We investigated the effectiveness […]
First-Of-Its-Kind Study Explains Why Some People Don’t Get COVID-19
JUN 20, 2024 – Authored by Marina Zhang via The Epoch Times Researchers have discovered why some people remain uninfected by the COVID-19 virus—even after their nasal cavities are exposed […]
Unlocking life-threatening COVID-19 through two types of inborn errors of type I IFNs
Jean-Laurent Casanova1,2,3,4,5 and Mark S. Anderson6,7, Published February 1, 2023 – More infoView PDF Abstract Since 2003, rare inborn errors of human type I IFN immunity have been discovered, each underlying a few severe […]
No evidence of durable trained immunity after two doses of adenovirus-vectored or mRNA COVID-19 vaccines
Natalie E. Stevens,1,2 Feargal J. Ryan,1,2 Nicole L. Messina,3,4 Stephen J. Blake,1,2 Todd S. Norton,1 Susie Germano,3 Jane James,1 Georgina L. Eden,1 Yee C. Tee,1,2 Miriam A. Lynn,1,2 Rochelle Botten,1 Simone E. Barry,5 Nigel Curtis,3,4 and David J. Lynn1,2 Published July 20, 2023 – September […]
Long COVID Now Looks like a Neurological Disease, Helping Doctors to Focus Treatments
The causes of long COVID, which disables millions, may come together in the brain and nervous system Stephani Sutherland March 1, 2023 Tara Ghormley has always been an overachiever. She […]