Authors: W. Glen Pyle Almost since the beginning of the COVID-19 pandemic, a piece of the SARS-CoV2 virus called the “spike protein” has drawn interest from researchers and healthcare professionals. […]
Evidence Shows that COVID-19 Attacks Blood Vessels
Authors: Carolyn Crist As researchers learn more about COVID-19, they’ve seen reports from patients about unusual rashes, blood clots, and strokes, which could all be linked to damaged blood vessels. […]
COVID-19 is, in the end, an endothelial disease
Authors: Peter Libby, Thomas Lüscher The vascular endothelium provides the crucial interface between the blood compartment and tissues, and displays a series of remarkable properties that normally maintain homeostasis. This tightly […]
COVID-19 Vasculopathy: Mounting Evidence for an Indirect Mechanism of Endothelial Injury
Authors: Roberto F. Nicosia,∗∗ Giovanni Ligresti,† Nunzia Caporarello,‡ Shreeram Akilesh,∗ and Domenico Ribatti§ Patients with coronavirus disease 2019 (COVID-19) who are critically ill develop vascular complications characterized by thrombosis of small, medium, and large vessels. […]
Endothelial dysfunction contributes to COVID-19-associated vascular inflammation and coagulopathy
Authors: Jun Zhang 1, Kristen M Tecson 1, Peter A McCullough 1 2 3 Great attention has been paid to endothelial dysfunction (ED) in coronavirus disease 2019 (COVID-19). There is growing evidence to suggest that the angiotensin […]
Endothelial dysfunction in COVID-19: Current findings and therapeutic implications
Authors: Matthias P Nägele 1, Bernhard Haubner 1, Felix C Tanner 1, Frank Ruschitzka 1, Andreas J Flammer 2 Coronavirus disease 2019 (COVID-19) increases the risk of several non-pulmonary complications such as acute myocardial injury, renal failure or thromboembolic […]
Mutational Similarities Between SARS-CoV-2 and Its Predecessors
Authors: | Original story from University of Nebraska–Lincoln, Credit: Pete Linforth/ Pixabay New research from the University of Nebraska-Lincoln has shown that the mutations arising in the COVID-19-causing SARS-CoV-2 virus seem […]
How Precision Medicine, Genomics Research is Decoding COVID-19
Authors: Jessica Kent Studies have sought to discover why the disease affects some individuals more severely than others, how communities can reduce the spread of infection, and which states or […]
SARS-CoV-2 genomics and host cellular susceptibility factors of COVID-19
Authors: FENGYU ZHANG AND MICHAEL D WATERS Coronavirus disease 19 (COVID-19) caused by infection with a novel severe acute respiratory syndrome virus -2 (SARS-CoV-2) has evolved into a pandemic and […]
Primed” for Infection: Cells Damaged by Chronic Lung Disease Can Result in Severe COVID
Authors: TRANSLATIONAL GENOMICS RESEARCH INSTITUTE (TGEN) Results from a TGen-led international study suggest that SARS-CoV-2 takes advantage of genetic changes among patients with pre-existing lung diseases. The results of a study by […]