Alert — EU looking into new side effects of Vaccine…


Authors: By citizenfreepress.com Three new conditions reported by people after vaccination with shots from Pfizer and Moderna are being studied to assess if they may be possible side effects, Europe’s drug regulator said on Wednesday. Erythema multiforme, a form of allergic skin reaction; glomerulonephritis or kidney inflammation; and nephrotic syndrome, a renal disorder characterised by […]

Here’s Why Viral Vector Vaccines Don’t Alter DNA


— It’s pretty simple — they can’t Authors: by Veronica Hackethal, MD, MSc, Enterprise & Investigative Writer, MedPage Today March 12, 2021 Adenoviral vector vaccines have been in development for decades, but very few have been approved for use in humans. What does the history of adenoviral vector vaccine development tell us about their safety and their […]

More Dangerous Side Effects Potentially Linked To mRNA Vaccines, EU Warns


Authors: BY TYLER DURDEN As shares of MRNA-vaccine purveyors Moderna and BioNTech tumbled on Wednesday, Reuters reported that the EMA, the EU’s medicines regulator, is looking into new potential side effects from the still-experimental MRNA jabs, including suspicious skin reactions and kidney ailments. According to Reuters, three new conditions have been reported by a small number […]

New data on coronavirus vaccine effectiveness may be “a wakeup call”


Authors: Caitlin Owens A new preprint study that raises concerns about the mRNA vaccines’ effectiveness against Delta — particularly Pfizer’s — has already grabbed the attention of top Biden administration officials. What they’re saying: The study found the Pfizer vaccine was only 42% effective against infection in July, when the Delta variant was dominant. “If that’s not a wakeup call, […]

What Do We Really Know About Adenovirus Vectors for Vaccines?


Authors: By Serena Marshall and Lara Salahi February 24, 2021 — The newest COVID shot uses an existing technology but one with lingering questions As the U.S. hits the half-million death mark from COVID-19 — a grim milestone that is equal to roughly the entire population of Atlanta and more than that of Miami — a new […]

Pros and Cons of Adenovirus-Based SARS-CoV-2 Vaccines


Authors: Eric J. Kremer1,∗ Main Text Most of us might be surprised by the rudimentary scientific rationale prevalent in the field of vaccine research just 50 years ago. For over a century after Louis Pasteur’s vaccine against rabies, approaches usually consisted of inactivating a virus, injecting it, and seeing if it protected the host. Unlike […]

What are Adenovirus-Based Vaccines?


Authors: By Dr. Sanchari Sinha Dutta, Ph.D.Reviewed by Sophia Coveney, B.Sc. Adenoviruses are considered excellent vectors for delivering target antigens to mammalian hosts because of their capability to induce both innate and adaptive immune responses. Currently, adenovirus-based vaccines are used against a wide variety of pathogens, including Mycobacterium tuberculosis, human immunodeficiency virus (HIV), and Plasmodium falciparum. What are adenoviruses? Adenoviruses are […]

Adenovirus-vectored Vaccines for COVID-19 – How Do They Work?


Authors: Heather D. Marshall, PhD | Vito Iacoviello, MD Viruses are genetic material surrounded by a protein shell with the ability to infect cells, highjack cellular machinery, and make copies of themselves. Viruses are also detected by the immune system and stimulate innate and adaptive immune responses and quite often, potent immunological memory that protects the host […]

Severe covid-19 pneumonia: pathogenesis and clinical management


Authors: Amy H Attaway, assistant professor of medicine, associate director, COPD center1,  Rachel G Scheraga, assistant professor of medicine1 2,  Adarsh Bhimraj, head, section of neurological infections; staff, infectious diseases1,  Michelle Biehl, associate staff, pulmonary and critical care medicine; director, post ICU recovery clinic1,  Umur Hatipoğlu, associate professor of medicine; director, respiratory therapy; director, COPD center1 […]

Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection in Children and Adolescents A Systematic Review


Authors: Riccardo Castagnoli, MD1,2; Martina Votto, MD1,2; Amelia Licari, MD1,2; et al Key Points Question  What are the clinical features of pediatric patients with coronavirus disease 2019 (COVID-19)? Findings  In this systematic review of 18 studies with 1065 participants, most pediatric patients with SARS-CoV-2 infection presented with fever, dry cough, and fatigue or were asymptomatic; 1 infant presented with pneumonia, complicated by shock and kidney failure, […]