Therapeutic potential of convalescent plasma and hyperimmune immunoglobulins against SARS-CoV-2 BQ.1, BQ.1.1, and XBB variants


Lorenza Bellusci, Hana Golding, and Surender Khurana Journal of Clinical Investigation Published 2023 – More infoView PDF  Convalescent plasma (CP) and hyperimmune intravenous immunoglobulins (IVIGs) are routinely used to treat patients with COVID-19. SARS-CoV-2 Omicron variants continue to evolve, generating multiple sublineages with increased transmissibility and antibody-escape mutations (1, 2). Several Omicron lineages that are currently circulating (BA.4, BA.5, […]

Bivalent Covid-19 Vaccines — A Cautionary Tale .


List of authors. Paul A. Offit, M.Dt of authors. Paul A. Offit, M.D New England Journal of Medicine January 23, 2023 in Wuhan, China. Two months later, the original strain of SARS-CoV-2, called the Wuhan-1 or ancestral strain, was isolated and sequenced. It was now possible to make a vaccine. All the vaccines, including the […]

Bivalent Covid-19 Vaccines — A Cautionary Tale.


List of authors. Paul A. Offit, M.D New England Journal of Medicine January 23, 2023 in Wuhan, China. Two months later, the original strain of SARS-CoV-2, called the Wuhan-1 or ancestral strain, was isolated and sequenced. It was now possible to make a vaccine. All the vaccines, including the mRNA vaccines made by Pfizer–BioNTech and […]

What COVID-19 variants are going around in November 2022?


Authors: Nebraska Medicine November 1, 2022 There are currently more than 37,000 cases reported in the United States per day, with test positivity of 8.6%. When test positivity is above 5%, transmission is considered uncontrolled. There are more than 340 deaths per day, and hospitalizations have increased 8% over the last two weeks.  What COVID-19 variant […]

Omicron’s Mutations Impaired Vaccine Effectiveness, CDC Says


Authors: Madison Muller  August 25, 2022 Bloomberg Almost 40% of people hospitalized in the US with the Covid subvariant that circulated this spring were vaccinated and boosted, highlighting how new strains have mutated to more readily escape the immunity offered by current shots. The findings from scientists at the US Centers for Disease Control and […]

Omicron is considered a milder coronavirus, but scientists aren’t so sure


Authors: Melissa Healy August 13, 2022 la times For more than two years, Cathy Baron and Sara Alicia Costa managed to duck the coronavirus. But despite their being fully vaccinated and boosted, the Omicron variant finally caught them. Baron is an actress and dance instructor who lives in Santa Monica. Costa is an architect in Austin, […]

Two new Omicron COVID subvariants BA.4 and BA.5 being analyzed by WHO


Only a few dozen cases of BA.4 and BA.5 have been reported to the global GISAID database, according to WHO Authors: Jennifer Rigby Reuters April 11, 2022 The World Health Organization said on Monday it is tracking a few dozen cases of two new sub-variants of the highly transmissible Omicron strain of the coronavirus to […]