John Murphy, M.D., MPH, DPH President Covid-19 long-haul Foundation Coronavirus disease 2019 (COVID‑19), caused by severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2), emerged in late 2019 as a global respiratory […]
Blackout Syndromes in Long-COVID: Etiology, Physiology, Pathology, and Clinical Determinants
John Murphy, M.D., M.P.H., DPH, President The Covid Long-haul Foundation AbstractPersistent transient loss of consciousness and pre-syncope (“blackout phenomena”) are increasingly recognized sequelae in patients with post-acute sequelae of SARS-CoV-2 […]
The Hidden Scourge: Depression and PTSD in Long-COVID Survivors
John Murphy, CEO The Covid Long-haul foundation. Introduction The enduring psychiatric sequelae of SARS-CoV-2 infection remain a defining, yet insufficiently understood, public health challenge of the COVID-19 pandemic. Long-COVID — […]
Chronic Inflammation Pathways Identified in Long COVID
I. Persistent Cytokine-Driven Inflammatory Signaling I.A. IL-6–Centered Inflammatory Axis Interleukin-6 (IL-6) has emerged as one of the most consistently elevated cytokines in Long COVID cohorts, serving as a central node […]
SARS-CoV-2–Associated Injury to Human Epithelial Tissues
Authors: John Murphy, M.D., MPH, DPH. ,Affiliations: President COVID-19 Long-haul FoundationAbstract: 250 words Abstract BackgroundSARS-CoV-2 infection produces multisystem disease with prominent epithelial involvement extending beyond the respiratory tract. Increasing evidence […]
Study Shows Structural Differences In COVID Patients Months After Infection, Even Among Those Who ‘Feel Fine’
In A Nutshell Brain scans of people who had COVID-19 show differences in brain structure months after infection, according to a small study from Australia. Even people who feel fully […]
You Recovered From COVID, But Did Your Brain? New Scans Raise Questions
Research led by Kiran Thapaliya (Griffith University) Study Shows Structural Differences In COVID Patients Months After Infection, Even Among Those Who ‘Feel Fine’ In A Nutshell Brain scans of people […]
The Motor Neuron Disease Spectrum
John Murphy, M.D., MPH, DPH, President The Covid-19 Long-haul Foundation Abstract Motor neuron diseases (MNDs) comprise a heterogeneous spectrum of neurodegenerative and immune-mediated disorders characterized by selective vulnerability of upper […]
Post–COVID-19 Immune Dysregulation and the Emergence of Methicillin-Resistant Staphylococcus aureus
John Murphy, M.D., MPH, DPH, President COVID-19 Long-haul Foundation Abstract The coronavirus disease 2019 (COVID‑19) pandemic has reshaped the global landscape of infectious diseases in ways that extend far beyond […]
Long COVID and Speech-Language Pathology: Etiology, Pathology, Clinical Observations, Progression, Treatment, and Prognosis
John Murphy, M.D., MPH, DPH, President COVID-19 Long-haul Foundation Abstract Long COVID—also called post-COVID-19 condition or post-acute sequelae of SARS-CoV-2 infection (PASC)—is a multisystem disorder that commonly produces persistent neurological, […]