Scientists uncover biological cause of Long COVID brain fog in major breakthrough

March 3, 2026 | John Murphy | Leave a Comment

Scientists uncover biological cause of Long COVID brain fog in major breakthrough

By Theo Farrant New research offers what scientists describe as the first biological evidence of Long COVID brain fog. Scientists in Japan have identified a potential biological cause of Long COVID brain fog,…[...]

March 2, 2026 | John Murphy | Leave a Comment

Research highlighting chronic inflammation opens path to treating illness that affects millions of Americans

A new study from investigators at Harvard and Beth Israel Deaconess Medical Center sheds light on why some people never fully recover from COVID-19. In research that analyzed blood samples…[...]

February 15, 2026 | John Murphy | Leave a Comment

Blackout Syndromes in Long-COVID: Etiology, Physiology, Pathology, and Clinical Determinants

John Murphy, M.D., M.P.H., DPH, President The Covid Long-haul Foundation AbstractPersistent transient loss of consciousness and pre-syncope (“blackout phenomena”) are increasingly recognized sequelae in patients with post-acute sequelae of SARS-CoV-2…[...]

December 23, 2025 | John Murphy | Leave a Comment

Inflammation: The Molecular Convergence of Gout, COVID-19, and Uric Acid Metabolism

Inflammation is not merely a symptom—it is a biological imperative. It orchestrates the body’s defense against infection, injury, and metabolic imbalance. Yet when dysregulated, inflammation becomes a crucible for chronic…[...]

August 27, 2025 | John Murphy | Leave a Comment

Long covid patients are desperate for treatments. These trials may help.

By Richard Sima The Washington Post Five years since the pandemic began, millions of people are still grappling with long COVID, even as new patients are joining their ranks. “Considering…[...]

August 8, 2025 | John Murphy | Leave a Comment

COVID-19 coagulopathy, thrombosis, and bleeding

Noel C. Chan, Jeffrey I. Weitz, Blood (2020) 136 (4): 381–383.https://doi.org/10.1182/blood.2020007335 In this issue of Blood, Al-Samkari et al expand our understanding of thrombosis and bleeding risks and their predictors in hospitalized patients with…[...]

May 25, 2025 | John Murphy | Leave a Comment

Post-COVID-19 Inflammatory Arthritis Treated With Upadacitinib: A Case Report

Cherie S. Zhi • Ami Ben-Artzi, DOI: 10.7759/cureus.78799 Abstract Two patients who developed inflammatory arthritis following COVID-19 infection are presented, characterized by arthralgias, arthritis, and elevated markers of inflammation (C-reactive protein). Both patients…[...]

January 11, 2025 | John Murphy | Leave a Comment

Musculoskeletal Manifestations of COVID-19: Currently Described Clinical Symptoms and Multimodality Imaging Findings

Imran M. Omar , Jennifer S. Weaver, Jonathan D. Samet, et. al. https://doi.org/10.1148/rg.220036 Abstract COVID-19, the clinical syndrome produced by infection with SARS-CoV-2, can result in multisystem organ dysfunction, including respiratory failure and hypercoagulability,…[...]

November 16, 2024 | John Murphy | Leave a Comment

Cutting Edge: Hyperinflammatory Monocytes Expressing CD56 Abound in Severe COVID-19 Patients

Stefania Campana; Claudia De Pasquale; Giacomo Sidoti Migliore;, et. al. J Immunol (2022) 209 (4): 655–659. https://doi.org/10.4049/jimmunol.2200021 Abstract Proinflammatory monocytes play a preponderant role in the development of a cytokine storm…[...]