Category: Kidney

COVID-19 and chronic kidney disease: a comprehensive review

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Authors: Inah Maria D. Pecly,1Rafael B. Azevedo,1Elizabeth S. Muxfeldt,1,2Bruna G. Botelho,1Gabriela G. Albuquerque,1Pedro Henrique P. Diniz,1Rodrigo Silva,1 and Cibele I. S. Rodrigues3 J Bras Nefrol. 2021 Jul-Sep; 43(3): 383–399.Published online 2021 Apr 9. doi: 10.1590/2175-8239-JBN-2020-0203PMCID: PMC8428633PMID: 33836039 Abstract Kidney impairment in hospitalized patients with SARS-CoV-2 infection is associated with increased in-hospital mortality and worse clinical evolution, raising concerns towards patients with chronic […]

Review of COVID-19, part 1: Abdominal manifestations in adults and multisystem inflammatory syndrome in children

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Authors: Devaraju Kanmaniraja,a,⁎ Jessica Kurian,a Justin Holder,a Molly Somberg Gunther,a Victoria Chernyak,b Kevin Hsu,a Jimmy Lee,a Andrew Mcclelland,a Shira E. Slasky,a Jenna Le,a and Zina J. Riccia Abstract The coronavirus disease 2019 (COVID -19) pandemic caused by the novel severe acute respiratory syndrome coronavirus (SARS-CoV-2) has affected almost every country in the world, resulting in severe morbidity, mortality and economic hardship, and altering the landscape of […]

Study examines the effects of COVID-19 on human kidney cells

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Date: June 10, 2021Source:American Society of Nephrology Summary: The virus that causes COVID-19 can infect and replicate in human kidney cells, but this does not typically lead to cell death. Kidney cells that already have features of injury may be more easily infected and develop additional injury. Researchers have studied human kidney cells in the […]

Another Hidden Covid Risk: Lingering Kidney Problems

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September 1, 2021in News Since the beginning of the pandemic, doctors have found that people who become very ill with Covid-19 often experience kidney problems, not just the lung impairments that are the hallmark of the illness. Now, a large study suggests that kidney issues can last for months after patients recover from the initial infection, and may lead […]

How does coronavirus kill? Clinicians trace a ferocious rampage through the body, from brain to toes

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Authors: By Meredith Wadman, Jennifer Couzin-Frankel, Jocelyn Kaiser, Catherine MatacicApr. 17, 2020 , 6:45 PM On rounds in a 20-bed intensive care unit one recent day, physician Joshua Denson assessed two patients with seizures, many with respiratory failure and others whose kidneys were on a dangerous downhill slide. Days earlier, his rounds had been interrupted as his team tried, […]

Clinical determinants of the severity of COVID-19: A systematic review and meta-analysis

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Authors: Xinyang Li, Xianrui Zhong, Yongbo Wang, Xiantao Zeng, Ting Luo, Qing Liu  Published: May 3, 2021 Abstract Objective We aimed to systematically identify the possible risk factors responsible for severe cases. Methods We searched PubMed, Embase, Web of science and Cochrane Library for epidemiological studies of confirmed COVID-19, which include information about clinical characteristics […]

Pathological findings in organs and tissues of patients with COVID-19: A systematic review

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Authors: Sasha Peiris 1 2, Hector Mesa 3, Agnes Aysola 4, Juan Manivel 5, Joao Toledo 1 2, Marcio Borges-Sa 6, Sylvain Aldighieri 1 2, Ludovic Reveiz 2 7 Abstract Background: Coronavirus disease (COVID-19) is the pandemic caused by SARS-CoV-2 that has caused more than 2.2 million deaths worldwide. We summarize the reported pathologic findings on biopsy and autopsy in patients with severe/fatal COVID-19 and documented the presence and/or effect of SARS-CoV-2 in all organs. […]

Pathophysiology of COVID-19:

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Mechanisms Underlying Disease Severity and Progression Authors: Mary Kathryn Bohn,1,2, Alexandra Hall,1 Lusia Sepiashvili,1,2, Benjamin Jung,1,2 Shannon, Steele,1 and Khosrow Adeli1,2,3 The global epidemiology of coronavirus disease 2019 (COVID-19) suggests a wide spectrum of clinical severity, ranging from asymptomatic to fatal. Although the clinical and laboratory characteristics of COVID-19 patients have been well characterized, the […]

High sensitivity troponin and COVID-19 outcomes

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Authors: Nikolaos Papageorgiou,a,bCatrin Sohrabi,aDavid Prieto Merino,c,dAngelos Tyrlis,aAbed Elfattah Atieh,aBunny Saberwal,aWei-Yao Lim,aAntonio Creta,aMohammed Khanji,aReni Rusinova,aBashistraj Chooneea,aRaj Khiani,d,eNadeev Wijesuriya,e,fAnna Chow,e,fHaroun Butt,e,fStefan Browne,e,fNikhil Joshi,e,fJamie Kay,e,fSyed Ahsan,a and Rui Providenciaa,g Abstract Background Recent reports have demonstrated high troponin levels in patients affected with COVID-19. In the present study, we aimed to determine the association between admission and peak troponin levels and […]

Long covid: Damage to multiple organs presents in young, low risk patients

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Authors: Gareth Iacobucci BMJ 2020; 371 doi: https://doi.org/10.1136/bmj.m4470 (Published 17 November 2020)Cite this as: BMJ 2020;371:m4470 Young, low risk patients with ongoing symptoms of covid-19 had signs of damage to multiple organs four months after initially being infected, a preprint study has suggested.1 Initial data from 201 patients suggest that almost 70% had impairments in one or more organs four months after […]