Category: C-reactive Protein

Dynamic Assessment of Hematological Parameters as Predictive Biomarkers for Disease Severity and Prognosis in COVID-19 Patients: A Longitudinal Study

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Aparna P. Patange • Jabbar V. Desai • Bhupal Pujari • Aparna Marwah • Animesh Dey, Published: July 01, 2024, DOI: 10.7759/cureus.63593  Abstract Background: The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has led to substantial morbidity and mortality worldwide. Hematological abnormalities are common in COVID-19 patients and play a significant role in disease pathogenesis and prognosis. Objective: […]

The knowns and unknowns of long COVID-19: from mechanisms to therapeutical approaches

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Roxana Gheorghita1,2Iuliana Soldanescu3Andrei Lobiuc2 , et. al., Front. Immunol., 03 March 2024, Sec. Viral Immunology, Volume 15 – 2024 | https://doi.org/10.3389/fimmu.2024.1344086 The coronavirus disease 2019 (COVID-19) pandemic caused by SARS-CoV-2 has been defined as the greatest global health and socioeconomic crisis of modern times. While most people recover after being infected with the virus, a significant […]

Acute blood biomarker profiles predict cognitive deficits 6 and 12 months after COVID-19 hospitalization

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Maxime Taquet, Zuzanna Skorniewska, Adam Hampshire, James D. Chalmers, Ling-Pei Ho, Alex Horsley, Michael Marks, Krisnah Poinasamy, Betty Raman, Olivia C. Leavy, Matthew Richardson, Omer Elneima, Hamish J. C. McAuley, Aarti Shikotra, Amisha Singapuri, Marco Sereno, Ruth M. Saunders, Victoria C. Harris, Linzy Houchen-Wolloff, Neil J. Greening, Parisa Mansoori, Ewen M. Harrison, Annemarie B. Docherty, Nazir I. Lone, PHOSP-COVID Study Collaborative Group,  Nature Medicine (August 2023)  Abstract Post-COVID cognitive deficits, including ‘brain fog’, are clinically complex, with both objective and […]

Neurological manifestations of post-acute sequelae of COVID-19: which liquid biomarker should we use?

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Dominique Comeau1† Mykella Martin2† Gilles A. Robichaud3,4,5 Ludivine Chamard-Witkowski2,6*1Dr. Georges-L. Long COVID syndrome, also known as post-acute sequelae of COVID-19 (PASC), is characterized by persistent symptoms lasting 3–12 weeks post SARS-CoV-2 infection. Patients suffering from PASC can display a myriad of symptoms that greatly diminish quality of life, the most frequent being neuropsychiatric. Thus, there is an eminent need […]

An overview of human proteins and genes involved in SARS-CoV-2 infection

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Zohreh Jahanafrooz,a,⁎ Zhishan Chen,b Jiandong Bao,c Hongzhi Li,d Loren Lipworth,b and Xingyi Guob,e,⁎Gene. 2022 Jan 15; 808: 145963. Published online 2021 Sep 14. doi: 10.1016/j.gene.2021.145963 PMCID: PMC8437745PMID: 34530086 Graphical abstract A summarized view of recent findings of host proteins interacting with SARS-CoV-2 and genes containing associated variants with COVID-19 susceptibility and severity. The left side of the figure (A) shows host protein interactors (blue wrote) for […]

Acute blood biomarker profiles predict cognitive deficits 6 and 12 months after COVID-19 hospitalization

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Maxime Taquet, Zuzanna Skorniewska, Adam Hampshire, James D. Chalmers, Ling-Pei Ho, Alex Horsley, Michael Marks, Krisnah Poinasamy, Betty Raman, Olivia C. Leavy, Matthew Richardson, Omer Elneima, Hamish J. C. McAuley, Aarti Shikotra, Amisha Singapuri, Marco Sereno, Ruth M. Saunders, Victoria C. Harris, Linzy Houchen-Wolloff, Neil J. Greening, Parisa Mansoori, Ewen M. Harrison, Annemarie B. Docherty, Nazir I. Lone, PHOSP-COVID Study Collaborative Group Nature Medicine (August 2023)  Abstract Post-COVID cognitive deficits, including ‘brain fog’, are clinically complex, with both objective and […]

COVID-19: A Global Threat to the Nervous System

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Authors: Igor J. Koralnik MD,Kenneth L. Tyler MD 07 June 2020 Annals of NeurologyVolume 88, Issue 1 p. 1-11 Abstract In less than 6 months, the severe acute respiratory syndrome-coronavirus type 2 (SARS-CoV-2) has spread worldwide infecting nearly 6 million people and killing over 350,000. Initially thought to be restricted to the respiratory system, we now […]

The Impact of Initial COVID-19 Episode Inflammation Among Adults on Mortality Within 12 Months Post-hospital Discharge

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Authors: Arch G. Mainous III1,2*, Benjamin J. Rooks1 and Frank A. Orlando1 May 12, 2022 Frontiers in Medicine Background: Inflammation in the initial COVID-19 episode may be associated with post-recovery mortality. The goal of this study was to determine the relationship between systemic inflammation in COVID-19 hospitalized adults and mortality after recovery from COVID-19. Methods: An analysis of electronic health […]

Acute Mesenteric Ischemia in COVID-19 Patients

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Authors: Dragos Serban 1,2,*† , Laura Carina Tribus 3,4,†, Geta Vancea 1,5,† , Anca Pantea Stoian, Ana Maria Dascalu 1,* Andra Iulia Suceveanu 6Ciprian Tanasescu 7,8, Andreea Cristina Costea 9 Mihail Silviu Tudosie 1, Corneliu Tudor 2, Gabriel Andrei Gangura 1,10, Lucian Duta 2 and Daniel Ovidiu Costea 6,11, Abstract: Acute mesenteric ischemia is a […]

Review of Mesenteric Ischemia in COVID-19 Patients

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Authors: Amit Gupta, Oshin Sharma, Kandhala Srikanth, Rahul Mishra, Amoli Tandon & Deepak Rajput  Indian Journal of Surgery (2022) Published: 11 March 2022 Abstract The new coronavirus (COVID-19) infection, first detected in Wuhan, China in 2019 has become a pandemic that has spread to nearly every country in the world. Through October 11, 2021, more than 23 billion confirmed cases and 4.8 million […]