Authors: COVID-19 pathophysiology: A review Koichi Yuki,⁎ Miho Fujiogi, and Sophia Koutsogiannaki Abstract In December 2019, a novel coronavirus, now named as SARS-CoV-2, caused a series of acute atypical respiratory diseases in […]
What Does COVID Do to Your Blood?
Authors: Panagis Galiatsatos, M.D., M.H.S., Robert Brodsky, M.D. COVID-19 is a very complex illness. The coronavirus that causes COVID-19 attacks the body in many different ways, ranging from mild to […]
Platelets Promote Thromboinflammation in SARS-CoV-2 Pneumonia
Authors: Francesco Taus, Gianluca Salvagno, Stefania Canè, Cristiano Fava, Fulvia Mazzaferri, Elena Carrara, Varvara Petrova, Roza Maria Barouni, Francesco Dima, Andrea Dalbeni, Simone Romano, Abstract Objective: Pulmonary thrombosis is observed in severe acute respiratory syndrome coronavirus 2 pneumonia. Aim was […]
Increased complement activation is a distinctive feature of severe SARS-CoV-2 infection
Authors: Lina Ma1, View ORCID ProfileSanjaya K. Sahu1, View ORCID ProfileMarlene Cano1, Vasanthan Kuppuswamy2, Jamal Bajwa1,3, View ORCID ProfileJa’Nia McPhatter1,4 Complement activation has been implicated in the pathogenesis of severe SARS-CoV-2 infection. However, it remains […]
Sars cov 2 drives jak1 2 dependent local complement hyperactivation
Authors: Patients with coronavirus disease 2019 (COVID-19) present a wide range of acute clinical manifestations affecting the lungs, liver, kidneys and gut. Angiotensin converting enzyme (ACE) 2, the best-characterized entry […]
SARS-CoV-2 spike protein-mediated cell signaling in lung vascular cells
Authors: Yuichiro J. Suzuki,a,⁎ Sofia I. Nikolaienko,b Vyacheslav A. Dibrova,b Yulia V. Dibrova,b Volodymyr M. Vasylyk,c Mykhailo Y. Novikov,d Nataliia V. Shults,a and Sergiy G. Gychkab Currently, the world is suffering from the pandemic of coronavirus disease 2019 […]
COVID-19 Autopsies Put Endothelial Damage, Angiogenesis in the Spotlight
Authors: L.A. McKeown NEWSDaily News COVID-19 Autopsies Put Endothelial Damage, Angiogenesis in the Spotlight The still-forming picture suggests significantly more new-vessel growth in the lung than would be expected from […]
The Thorny Problem Of COVID-19 Vaccines And Spike Proteins
Authors: W. Glen Pyle Almost since the beginning of the COVID-19 pandemic, a piece of the SARS-CoV2 virus called the “spike protein” has drawn interest from researchers and healthcare professionals. […]
Evidence Shows that COVID-19 Attacks Blood Vessels
Authors: Carolyn Crist As researchers learn more about COVID-19, they’ve seen reports from patients about unusual rashes, blood clots, and strokes, which could all be linked to damaged blood vessels. […]
COVID-19 Vasculopathy: Mounting Evidence for an Indirect Mechanism of Endothelial Injury
Authors: Roberto F. Nicosia,∗∗ Giovanni Ligresti,† Nunzia Caporarello,‡ Shreeram Akilesh,∗ and Domenico Ribatti§ Patients with coronavirus disease 2019 (COVID-19) who are critically ill develop vascular complications characterized by thrombosis of small, medium, and large vessels. […]