Complement system causes cell damage in long Covid


January, 2024, Source: University of Zurich Science Daily Summary: Long Covid patients suffer from chronic symptoms such as fatigue or shortness of breath. As researchers have discovered, this is to some extent due to a part of our immune system called the complement system. The study identified a pattern in the blood proteins that will […]

Prior COVID-19 Infection May Protect Against Common Colds: Study


SATURDAY, JUN 15, 2024 –Authored by Zachary Stieber via The Epoch Times  People with a history of COVID-19 infection are better protected against common colds than people who received a COVID-19 vaccine, according to a new study. Infection and vaccination triggered similar antibody responses in study participants, but T cell responses targeting endemic coronaviruses, which […]

Long Covid Defined


Authors: E. Wesley Ely, M.D., M.P.H. https://orcid.org/0000-0003-3957-2172, Lisa M. Brown, M.P.H., and Harvey V. Fineberg, M.D., Ph.D., for the National Academies of Sciences, Engineering, and Medicine Committee on Examining the Working Definition for Long Covid, DOI: 10.1056/NEJMsb2408466 The Covid-19 pandemic has been perceived mainly as a dangerous acute outbreak of infection that killed more than a million people in the United States and 7 million worldwide.1,2 However, […]

The blood holds clues to understanding long COVID


The search for biomarkers could eventually lead scientists to tests and treatments By Meghan Rosen, MARCH 4, 2024 AT 9:00 AM Science News When I talk to immunologist Paul Morgan, he’s on the hunt for potentially life-altering drugs.  He’s got a call with a pharmaceutical company planned in the next half hour. His goal: persuade the company to […]

SARS-CoV-2 infection modifies the transcriptome of the megakaryocytes in the bone marrow


Isabelle Allaeys, Guillaume Lemaire, Mickaël Leclercq, et. al. Blood Adv (2024) 8 (11): 2777–2789. Megakaryocytes (MKs), integral to platelet production, predominantly reside in the bone marrow (BM) and undergo regulated fragmentation within sinusoid vessels to release platelets into the bloodstream. Inflammatory states and infections influence MK transcription, potentially affecting platelet functionality. Notably, COVID-19 has been associated […]

The blood holds clues to understanding long COVID


The search for biomarkers could eventually lead scientists to tests and treatments By Meghan Rosen, MARCH 4, 2024 Science News When I talk to immunologist Paul Morgan, he’s on the hunt for potentially life-altering drugs.  He’s got a call with a pharmaceutical company planned in the next half hour. His goal: persuade the company to supply his lab […]

The Neurological Implications of COVID-19: A Comprehensive Narrative Review


Ithamar Cheyne • Venmanassery Sreejan Gopinath • Neeharika Muppa , et. al., May 15, 2024, DOI: 10.7759/ cureus.60376  Abstract The COVID-19 pandemic caused by the coronavirus SARS-CoV-2 revealed a huge number of problems as well as discoveries in medicine, notably, regarding the effects of the virus on the central nervous system (CNS) and peripheral nervous system (PNS). This paper is a narrative […]

New study reveals insights into COVID-19 antibody response durability


University of Maryland School of Medicine, 2024 Researchers at the Institute of Human Virology (IHV) at the University of Maryland School of Medicine have published a new study in the Journal of Infectious Diseases investigating the antibody response following SARS-CoV-2 infection. Long-lived plasma cells are responsible for durable antibody responses that persist for decades after immunization or infection. For example, infection […]

People with long COVID have distinct patterns of inflammation detectable in the blood, which could potentially be targeted with immune therapies.


Findings from the largest UK study of patients hospitalized with SARS-CoV-2 infection show that long COVID leads to ongoing inflammation which can be detected in the blood. In an analysis of more than 650 people who had been hospitalized with severe COVID-19, patients with prolonged symptoms showed evidence of immune system activation. The exact pattern […]

COVID and Leukemia: What’s the Connection?


Written by Lisa Mulcahy, May 31, 2023 – WebMD Once you test negative after a bout with COVID-19, it’s a great idea to get a full health screening. This is especially important for people who are at risk for, or have, blood cancers like leukemia.  If you have blood cancer, you need to have a clear picture […]