Comparison between RT-qPCR for SARS-CoV-2 and expanded triage in sputum of symptomatic and asymptomatic COVID-19 subjects in Ecuador

Authors: Ariel Torres, Martha Fors, Tamaris Rivero, Karina Pantoja & Santiago Ballaz  BMC Infectious Diseases volume 21, Article number: 558 (2021)  Abstract Background The quantitative reverse transcriptase-polymerase chain reaction (RT-qPCR) effectively detects the SARS-COV-2 virus. SARS-CoV-2 Nevertheless, some critical gaps…[...]

Read More

Pathological findings in organs and tissues of patients with COVID-19: A systematic review

Authors: Sasha Peiris 1 2, Hector Mesa 3, Agnes Aysola 4, Juan Manivel 5, Joao Toledo 1 2, Marcio Borges-Sa 6, Sylvain Aldighieri 1 2, Ludovic Reveiz 2 7 Abstract Background: Coronavirus disease (COVID-19) is the pandemic caused by SARS-CoV-2 that has caused more than 2.2 million deaths worldwide. We…[...]

Read More

Cytokeratin 18 cell death assays as biomarkers for quantification of apoptosis and necrosis in COVID-19: a prospective, observational study

Authors: Brandon Michael Henry1, http://orcid.org/0000-0002-1211-8247Isaac Cheruiyot2, Stefanie W Benoit3,4, Fabian Sanchis-Gomar5,6, http://orcid.org/0000-0001-9523-9054Giuseppe Lippi7, Justin Benoit8 Correspondence to Dr Brandon Michael Henry, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA; Abstract Background The mechanism by which SARS-CoV-2 triggers…[...]

Read More

Overweight/obesity as the potentially most important lifestyle factor associated with signs of pneumonia in COVID-19

Authors: Vanessa Sacco ,Barbara Rauch ,Christina Gar,Stefanie Haschka,Anne L. Potzel,Stefanie Kern-Matschilles,Friederike Banning,Irina Benz,Mandy Meisel,Jochen Seissler,Andreas Lechner  Published: November 18, 2020 Abstract Objective The occurrence of pneumonia separates severe cases of COVID-19 from…[...]

Read More

Hyperglycemia in Acute COVID-19 is Characterized by Adipose Tissue Dysfunction and Insulin Resistance

Authors: Reiterer M, Rajan M, Gómez-Banoy N, Lau JD, Gomez-Escobar LG, Gilani A, Alvarez-Mulett S, Sholle ET, Chandar V, Bram Y, Hoffman K, Rubio-Navarro A, Uhl S, Shukla AP, Goyal P, tenOever BR, Alonso LC, Schwartz RE, Schenck EJ, Safford MM Abstract  COVID-19 has proven to be a metabolic…[...]

Read More

Blood molecular markers associated with COVID-19 immunopathology and multi-organ damage

Authors: Yan-Mei ChenYuanting ZhengYing YuYunzhi WangQingxia HuangFeng QianLei SunZhi-Gang SongZiyin ChenJinwen FengYanpeng AnJingcheng YangZhenqiang SuShanyue SunFahui DaiQinsheng ChenQinwei LuPengcheng LiYun LingZhong YangHuiru TangLeming ShiLi JinEdward C HolmesChen DingTong-Yu ZhuYong-Zhen Zhang…[...]

Read More

Circulating mitochondrial DNA is an early indicator of severe illness and mortality from COVID-19

Authors: Davide Scozzi,1Marlene Cano,2Lina Ma,2Dequan Zhou,1Ji Hong Zhu,1Jane A. O’Halloran,3Charles Goss,4Adriana M. Rauseo,3Zhiyi Liu,1Sanjaya K. Sahu,2Valentina Peritore,5Monica Rocco,6Alberto Ricci,7Rachele Amodeo,8Laura Aimati,8Mohsen Ibrahim,1,5Ramsey Hachem,2Daniel Kreisel,1Philip A. Mudd,9Hrishikesh S. Kulkarni,2,10 and Andrew E. Gelman1,11…[...]

Read More

C-Reactive Protein Level May Predict the Risk of COVID-19 Aggravation

Authors: Guyi Wang 1, Chenfang Wu 1, Quan Zhang 2, Fang Wu 3, Bo Yu 1, Jianlei Lv 2, Yiming Li 4, Tiao Li 5, Siye Zhang 1, Chao Wu 6 7 8, Guobao Wu 1, Yanjun Zhong 1Affiliations expand Abstract Background: Clinical findings indicated that a fraction of coronavirus disease 2019 (COVID-19) patients diagnosed as mild…[...]

Read More