Authors: Baher Al Abbasi 1, Pedro Torres 1, Fergie Ramos-Tuarez 2, Nakeya Dewaswala 1, Ahmed Abdallah 1, Kai Chen 1, Mohamed Abdul Qader 1, Riya Job 1, Samar Aboulenain 1, Karolina Dziadkowiec 1, Huzefa Bhopalwala 3, Jesus E Pino 2, Robert D Chait 2 Abstract Background: The number of fatalities due to coronavirus disease 2019 (COVID-19) […]
Inflammasome activation at the crux of severe COVID-19
Authors: Setu M. Vora,1,2Judy Lieberman,2,3 and Hao Wu1,2 Abstract The COVID-19 pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), results in life-threatening disease in a minority of patients, especially elderly […]
Mapping the human genetic architecture of COVID-19
COVID-19 Host Genetics Initiative, Nature (2021) Abstract The genetic makeup of an individual contributes to susceptibility and response to viral infection. While environmental, clinical and social factors play a role in […]
Body mass index and severity/fatality from coronavirus disease 2019: A nationwide epidemiological study in Korea
Authors: In Sook Kang , Kyoung Ae Kong Published: June 22, 2021 Abstract Obesity has been reported as a risk factor for severe coronavirus disease 2019 (COVID-19) in recent studies. However, […]
Simple blood test can tell whether patients will suffer from ‘long COVID’
Authors: by Study Finds AUGUST 15, 2021 CAMBRIDGE, England — A simple blood test for long COVID is on the horizon. Biological “fingerprints” can identify individuals with the debilitating syndrome, according […]
Associations between body-mass index and COVID-19 severity in 6·9 million people in England: a prospective, community-based, cohort study
Authors: Min Gao, MSc *, Carmen Piernas, PhD , Nerys M Astbury, PhD, Prof Julia Hippisley-Cox, FRCPProf Stephen O’Rahilly, FRS, Prof Paul Aveyard, FRCGP † Summary Background Obesity is a major risk factor […]
Lack of antibodies against seasonal coronavirus OC43 nucleocapsid protein identifies patients at risk of critical COVID-19
Authors: MartinDugasa1TanjaGrote-Westrickb1UtaMerledMichaelaFontenaylmAndreas E.KremerhFrankHansesijRichardVollenbergcEvaLorentzenbShilpaTiwari-BecklerdJérômeDucheminlSyrineEllouzelMarcelVetterhJuliaFürsthPhilippSchusterkTobiasBrixaClaudia M.DenkingerfgCarstenMüller-TidoweHartmutSchmidtc…JoachimKühnb1 Highlights Does prior infection with seasonal human coronavirus OC43 protect against critical COVID-19?• Findings: In an international multi-center study inpatients without anti-HCoV OC43 NP antibodies had an increased risk of […]
Attributes and predictors of long COVID
Authors: Carole H. Sudre, Benjamin Murray, Claire J. Steves Abstract Reports of long-lasting coronavirus disease 2019 (COVID-19) symptoms, the so-called ‘long COVID’, are rising but little is known about prevalence, risk factors […]
Can we predict the severe course of COVID-19 – a systematic review and meta-analysis of indicators of clinical outcome?
Authors: Stephan Katzenschlager ,Alexandra J. Zimmer ,Claudius Gottschalk, Jürgen Grafeneder,Stephani Schmitz, Sara Kraker, Marlene Ganslmeier, Amelie Muth, Alexander Seitel, Lena Maier-Hein, Andrea Benedetti, Jan Larmann, Markus A. Weigand, Sean McGrath , Claudia M. […]
COVID-19-Associated Bronchiectasis and Its Impact on Prognosis
Authors: Aasir M. Suliman, Bassel W. Bitar, Amer A. Farooqi, Anam M. Elarabi, Mohamed R. Aboukamar, Ahmed S. Abdulhadi Abstract Coronavirus disease 2019 (COVID-19), which initially emerged in Wuhan, China, has rapidly swept around the […]