Complement control for COVID-19
Authors: Markus Bosmann1,2,3,4,* The complement system is an integral part of innate immune defense. It consists of about 50 proteins in plasma, on cell surfaces, and inside host cells. The…[...]
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Eye scan could determine whether COVID patients will be ‘long haulers’
Authors: by Study Finds Long COVID” continues to confound doctors as patients still struggle with debilitating symptoms months after first being infection. A new study now suggests that COVID patients…[...]
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Decoding SARS-CoV-2 hijacking of host mitochondria in COVID-19 pathogenesis
Authors: Keshav K. Singh,* Gyaneshwer Chaubey,* Jake Y. Chen, and Prashanth Suravajhala Because of the ongoing pandemic around the world, the mechanisms underlying the SARS-CoV-2-induced COVID-19 are subject to intense investigation. Based on…[...]
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Decoding SARS-CoV-2 hijacking of host mitochondria in COVID-19 pathogenesis
Authors: Keshav K. Singh,* Gyaneshwer Chaubey,* Jake Y. Chen, and Prashanth Suravajhala Because of the ongoing pandemic around the world, the mechanisms underlying the SARS-CoV-2-induced COVID-19 are subject to intense investigation. Based on…[...]
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COVID-19 is, in the end, an endothelial disease
Authors: Peter Libby, Thomas Lüscher The vascular endothelium provides the crucial interface between the blood compartment and tissues, and displays a series of remarkable properties that normally maintain homeostasis. This tightly…[...]
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Endothelial dysfunction contributes to COVID-19-associated vascular inflammation and coagulopathy
Authors: Jun Zhang 1, Kristen M Tecson 1, Peter A McCullough 1 2 3 Great attention has been paid to endothelial dysfunction (ED) in coronavirus disease 2019 (COVID-19). There is growing evidence to suggest that the angiotensin…[...]
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What Is a Cytokine Storm? Doctors Explain How Some COVID-19 Patients’ Immune Systems Turn Deadly
Authors: Sarah Bradley The news cycle is heavily saturated with stress-inducing information about COVID-19, but one of the most worrying aspects so far has been the huge disparity in the way the novel…[...]
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COVID-19 cytokine storm: The anger of inflammation
Authors: Mehdi Mahmudpour 1, Jamshid Roozbeh 2, Mohsen Keshavarz 1, Shokrollah Farrokhi 3, Iraj Nabipour 4 Patients with COVID-19 who require ICU admission might have the cytokine storm. It is a state of out-of-control release of a variety of…[...]
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Cytokine Storm in COVID-19: The Current Evidence and Treatment Strategies
Authors: Yujun Tang,† Jiajia Liu,† Dingyi Zhang, Zhenghao Xu, Jinjun Ji,* and Chengping Wen* Severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2) is the pathogen that causes coronavirus disease 2019 (COVID-19). As of 25 May 2020, the…[...]
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SARS-CoV-2 infection: The role of cytokines in COVID-19 disease
Authors: Víctor J Costela-Ruiz 1, Rebeca Illescas-Montes 1, Jose M Puerta-Puerta 2, Concepción Ruiz 3, Lucia Melguizo-Rodríguez 1 COVID-19 disease, caused by infection with SARS-CoV-2, is related to a series of physiopathological mechanisms that mobilize a wide variety of…[...]
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