Category: Inflammation

Ileocecal Intussusception in the Era of Coronavirus Disease 2019 (COVID-19) Infection and Multisystem Inflammatory Syndrome in Children (MIS-C): A Case Report and Literature Review

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Niharika Alla • Thaer Abdul-Hadi • Florentina Litra: June 19, 2024, DOI: 10.7759/cureus.62731  Abstract Ileocecal intussusception (ICI) is the most common abdominal emergency and cause of intestinal obstruction in young children, carrying a high risk of mortality and morbidity. Enteric viral infectious and inflammatory syndromes are known triggers for intussusception (ileoileal and ileocolic) by causing mesenteric lymphoid hyperplasia that may act as […]

How wave of new dementias may be fueled by surprising culprit every home has been touched by

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By Maiya Focht, A new study has added fuel to concerns that America could face a surge in dementias in coming years and decades due to COVID.  The research found that nearly two-thirds of people over 65 who were hospitalized with the virus went on to suffer cognitive decline, which can be a precursor for dementia, weeks […]

Inflammation: The Body’s ‘Fire’ Burns Threats, But Things Go Wrong When It Smolders

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Authored by Flora Zhao via The Epoch Times Many people experience chronic inflammation without even knowing it, Arch G. Mainous III, a professor at the University of Florida (UF) College of Medicine, told The Epoch Times. A large-scale study published in Frontiers in Medicine in 2024 showed that among adults in the United States, almost 35 percent had […]

Pathophysiological, immunological, and inflammatory features of long COVID

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Karen Bohmwald1,2†Benjamín Diethelm-Varela1†Linmar Rodríguez-Guilarte1 , et. al., Front. Immunol., 27 February 2024, Sec. Viral Immunology, Volume 15 – 2024 | https://doi.org/10.3389/fimmu.2024.1341600 The COVID-19 pandemic continues to cause severe global disruption, resulting in significant excess mortality, overwhelming healthcare systems, and imposing substantial social and economic burdens on nations. While most of the attention and therapeutic efforts have […]

Improvement of immune dysregulation in individuals with long COVID at 24-months following SARS-CoV-2 infection

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Chansavath Phetsouphanh, Brendan Jacka, et. al., Nature Communications volume 15, Article number: 3315 (2024) Abstract This study investigates the humoral and cellular immune responses and health-related quality of life measures in individuals with mild to moderate long COVID (LC) compared to age and gender matched recovered COVID-19 controls (MC) over 24 months. LC participants show elevated nucleocapsid IgG levels at 3 months, […]

The underlying cause of Long COVID is still a puzzle

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The underlying cause of Long COVID is still a puzzle to researchers. But Akiko Iwasaki, PhD, Sterling Professor of Immunobiology and Molecular, Cellular, and Developmental Biology at Yale School of Medicine (YSM) and co-lead investigator of the Yale RECOVERY and Yale LISTEN studies, has theories. Iwasaki explains that Long COVID is an “umbrella term” and likely has “multiple mechanisms that are not […]

People with long COVID have distinct patterns of inflammation detectable in the blood, which could potentially be targeted with immune therapies.

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Findings from the largest UK study of patients hospitalized with SARS-CoV-2 infection show that long COVID leads to ongoing inflammation which can be detected in the blood. In an analysis of more than 650 people who had been hospitalized with severe COVID-19, patients with prolonged symptoms showed evidence of immune system activation. The exact pattern […]

Efficacy and Safety of Lithium Treatment in SARS-CoV-2 Infected Patients

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Carlos Spuch, 1 ,* † Marta López-García, 1 , 2 , † Tania Rivera-Baltanás, 1 ,  , et.al. Front Pharmacol. 2022; 13: 850583. Published online 2022 Apr 14. doi:  10.3389/fphar.2022.850583PMCID: PMC9046673PMID: 35496309 Abstract At the beginning of the pandemic, we observed that lithium carbonate had a positive effect on the recovery of severely ill patients with COVID-19. Lithium is able to inhibit the replication of several types of […]

Long COVID: Is there a kidney link?

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Raymond E. Garrett, Carlos H. Palacio, David Bar-Or: HYPOTHESIS AND THEORY article, Front. Med., 03 April 2023, Sec. Nephrology, Volume 10 – 2023 | https://doi.org/10.3389/fmed.2023.1138644 Metabolic causes such as altered bioenergetics and amino acid metabolism may play a major role in Long COVID. Renal-metabolic regulation is an integral part of these pathways but has not been […]

FDA System Unable To Identify Risk Of Heart Inflammation After COVID-19 Vaccination: Agency

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DEC 10, 2023 – Authored by Zachary Stieber via The Epoch Times  The U.S. Food and Drug Administration could not provide information on a confirmed side effect of the Pfizer COVID-19 vaccine, according to a newly disclosed document. FDA staffers said in the document, from 2021, that one of the agency’s top surveillance systems was unable […]