Category: Inflammation

The intersection of COVID-19 and autoimmunity

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Jason S. Knight,1 Roberto Caricchio,2 Jean-Laurent Casanova,3,4,5,6 Alexis J. Combes,7 Betty Diamond,8 Sharon E. Fox,9,10 David A. Hanauer,11 Judith A. James,12 Yogendra Kanthi,13 Virginia Ladd,14 Puja Mehta,15 Aaron M. Ring,16 Ignacio Sanz,17 Carlo Selmi,18,19 Russell P. Tracy,20 Paul J. Utz,21 Catriona A. Wagner,14 Julia Y. Wang,22 and William J. McCune1,Published October 28, 2021 – Free access | 10.1172/JCI154886 Acute COVID-19, caused by SARS-CoV-2, is characterized by diverse clinical presentations, ranging from asymptomatic infection to fatal respiratory […]

Systemic and organ-specific immune-related manifestations of COVID-19

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Manuel Ramos-Casals, Pilar Brito-Zerón & Xavier Mariette Nature Reviews Rheumatology volume 17, pages315–332 (2021) Cite this article Abstract Immune-related manifestations are increasingly recognized conditions in patients with COVID-19, with around 3,000 cases reported worldwide comprising more than 70 different systemic and organ-specific disorders. Although the inflammation caused by SARS-CoV-2 infection is predominantly centred on the respiratory system, some patients can develop an […]

COVID-19 Vagus Nerve Inflammation May Lead To Dysautonomia: New Study

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 Authored by Megan Redshaw  The Epoch Times AUG 2023 New data may provide answers for those experiencing persistent symptoms long after their bout with COVID-19 has ended. These may include fatigue, lightheadedness, brain fog, cognitive issues, gastrointestinal problems, heart palpitations, shortness of breath, or an inability to tolerate upright postures. A July 15 study published […]

Molecular mechanisms of COVID-19-induced pulmonary fibrosis and epithelial-mesenchymal transition

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Authors: Peng Pi1† Zhipeng Zeng1† Liqing Zeng1 Bing Han1 Xizhe Bai2 Shousheng Xu3*Front. Pharmacol., 03 August 2023, Sec. Respiratory Pharmacology, Volume 14 – 2023 | https://doi.org/10.3389/fphar.2023.1218059 As the outbreak of COVID-19 caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) first broke out in Hubei Province, China, at the end of 2019. It has brought great challenges and harms to global […]

COVID-19 Vaccines ‘May Trigger’ Rheumatic Inflammatory Diseases: Study

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OCT 15, 2023 – Authored by Marina Zhang via The Epoch Times  A new review suggests that COVID vaccines “may trigger” rheumatic immune-mediated inflammatory diseases, including arthritis, vasculitis, lupus, and adult-onset Still’s disease. On average, patients developed rheumatic diseases 11 days after vaccine administration, according to the study. Seventy-five (over 27 percent) of these patients experienced […]

Potential molecular mechanisms of chronic fatigue in long haul COVID and other viral diseases

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Carl Gunnar Gottschalk, Daniel Peterson, Jan Armstrong, Konstance Knox & Avik Roy  Infectious Agents and Cancer volume 18, Article number: 7 (2023) Cite this article, A Correction to this article was published on 24 April 2023 Abstract Historically, COVID-19 emerges as one of the most devastating diseases of humankind, which creates an unmanageable health crisis worldwide. Until now, this disease costs millions of lives and continues to paralyze […]

Long COVID scientists try to unravel blood clot mystery

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May 15, 202312:15 AM ET By Anil Oza, Rebecca Ramirez, Emily Kwong, Gabriel Spitzer, Margaret Cirino, Berly McCoy, https://www.npr.org/2023/05/10/1175217130/long-covid-scientists-try-to-unravel-blood-clot-mystery As part of studying long COVID, graduate researcher Bradley Wade Hamilton separates out microclots from blood platelets in a solution. The federal COVID-19 public health emergency ended last week, but millions in the U.S. — and across the globe — are still dealing […]

Serum vitamin D levels can be predictive of psoriasis flares up after COVID-19 vaccination: a retrospective case control study

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Emmanouil Karampinis1 George Goudouras1 Niki Ntavari1 Dimitrios Petrou Bogdanos2† Angeliki-Victoria Roussaki-Schulze1† Efterpi Zafiriou1*† Front. Med., 25 May 2023 Sec. Dermatology Volume 10 – 2023 | https://doi.org/10.3389/fmed.2023.1203426 Introduction: Many patients with chronic inflammatory dermatosis such as psoriasis usually ask about the safety of COVID-19 vaccination and if it would affect the course of their disease. Indeed, many case reports, case series and clinical […]

New onset and exacerbation of psoriasis after COVID-19 vaccination

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Nancy Wei, BA,a,∗ Mindy Kresch, BS,b Emily Elbogen, PA-C,c and Mark Lebwohl, MDc JAAD Case Rep. 2022 Jan; 19: 74–77. Published online 2021 Nov 29. doi: 10.1016/j.jdcr.2021.11.016 PMCID: PMC8628636 PMID: 34869811 Introduction The messenger RNA (mRNA)-1273 (Moderna) and BNT162b2 (Pfizer-BioNTech) vaccines were granted emergency use authorization during the ongoing COVID-19 pandemic by the United States Food and Drug Administration in December 2020.1 An adenoviral vector […]

COVID-19 can trigger auto-immune disorders-related antibodies, causing thrombosis and other complications

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SEPTEMBER 12, 2023 by Maria Fernanda Ziegler, FAPESP Medical Express An article published in npj Aging reveals that natural production of auto-antibodies increases with age, and that infection by SARS-CoV-2 can exacerbate production of auto-antibodies relating to auto-immune diseases, helping to explain why aging increases the chances of developing severe COVID-19. The study also discovered some of the factors that […]