Category: Severity

Posted on | Posted on John Murphy | Leave a Comment on Baricitinib for patients with severe COVID-19—time to change the standard of care?

Baricitinib for patients with severe COVID-19—time to change the standard of care?

AuthorsAlexander Supadya,c,d and Robert Zeiserb Lancet Respir Med. 2022 Feb 3doi: 10.1016/S2213-2600(22)00021-2 [Epub ahead of print]PMCID: PMC8813061PMID: 35123659 Mortality is high among patients with severe COVID-19 who require invasive mechanical ventilation (IMV) or extracorporeal membrane oxygenation (ECMO).1, 2 Therefore,…[...]

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Posted on | Posted on John Murphy | Leave a Comment on Risk of severe COVID-19 disease with ACE inhibitors and angiotensin receptor blockers: cohort study including 8.3 million people

Risk of severe COVID-19 disease with ACE inhibitors and angiotensin receptor blockers: cohort study including 8.3 million people

Julia Hippisley-Cox1, Duncan Young2,3, Carol Coupland4, Keith M Channon5, Pui San Tan6, David A Harrison7, Kathryn Rowan8,  Paul Aveyard6, Ian D Pavord9, Peter J Watkinson5,10Correspondence to Prof Julia Hippisley-Cox, Primary Care Health Sciences, University of Oxford, Oxford OX1  Abstract…[...]

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Posted on | Posted on John Murphy | Leave a Comment on Anosmia and dysgeusia in SARS-CoV-2 infection: incidence and effects on COVID-19 severity and mortality, and the possible pathobiology mechanisms – a systematic review and meta-analysis

Anosmia and dysgeusia in SARS-CoV-2 infection: incidence and effects on COVID-19 severity and mortality, and the possible pathobiology mechanisms – a systematic review and meta-analysis

Authors: Endang Mutiawati, Conceptualization, Data Curation, Resources, Validation, Writing – Original Draft Preparation, Writing – Review & Editing,a,1,2Marhami Fahriani, Conceptualization, Data Curation, Investigation, Methodology, Validation, Writing – Original Draft Preparation, Writing – Review & Editing,3Sukamto S. Mamada, Data Curation, Investigation, Validation, Writing – Review & Editing,4Jonny Karunia…[...]

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Posted on | Posted on John Murphy | Leave a Comment on Overweight/obesity as the potentially most important lifestyle factor associated with signs of pneumonia in COVID-19

Overweight/obesity as the potentially most important lifestyle factor associated with signs of pneumonia in COVID-19

Authors: Vanessa Sacco ,Barbara Rauch ,Christina Gar,Stefanie Haschka,Anne L. Potzel,Stefanie Kern-Matschilles,Friederike Banning,Irina Benz,Mandy Meisel,Jochen Seissler,Andreas Lechner  Published: November 18, 2020 Abstract Objective The occurrence of pneumonia separates severe cases of COVID-19 from…[...]

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Posted on | Posted on John Murphy | Leave a Comment on Role of DAMPs in respiratory virus-induced acute respiratory distress syndrome—with a preliminary reference to SARS-CoV-2 pneumonia

Role of DAMPs in respiratory virus-induced acute respiratory distress syndrome—with a preliminary reference to SARS-CoV-2 pneumonia

Review Article; Published: 17 June 2021 Authors: Walter Gottlieb Land Genes & Immunity volume 22, pages141–160 (2021 )Cite this article Abstract When surveying the current literature on COVID-19, the “cytokine storm” is considered to be…[...]

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Posted on | Posted on John Murphy | Leave a Comment on The Impact of the Covid 19 Pandemic on Cerebrovascular Disease: CORD-Papers-2021-06-28

The Impact of the Covid 19 Pandemic on Cerebrovascular Disease: CORD-Papers-2021-06-28

Abstract:            Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes a systemic disease that affects nearly all organ systems through infection and subsequent dysregulation of the vascular endothelium. One of the…[...]

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