Authors: Sarah C.P. Williams A study of antibody-producing B cells from patients who recovered from COVID-19 reveals a new cross-reactive antibody and what makes some B cells more effective at […]
Complement Anaphylatoxins and Inflammatory Cytokines as Prognostic Markers for COVID-19 Severity and In-Hospital Mortality
Authors: Bandar Alosaimi1,2, Ayman Mubarak3, Maaweya E. Hamed3, Abdullah Z. Almutairi4, Ahmed A. Alrashed5, Abdullah AlJuryyan6, Mushira Enani7,Faris Q. Alenzi8 and Wael Alturaiki9* COVID-19 severity due to innate immunity dysregulation accounts for prolonged hospitalization, critical complications, and mortality. […]
Sars cov 2 drives jak1 2 dependent local complement hyperactivation
Authors: Patients with coronavirus disease 2019 (COVID-19) present a wide range of acute clinical manifestations affecting the lungs, liver, kidneys and gut. Angiotensin converting enzyme (ACE) 2, the best-characterized entry […]
SARS-CoV-2-Specific Memory T Lymphocytes From COVID-19 Convalescent Donors: Identification, Biobanking, and Large-Scale Production for Adoptive Cell Therapy
Authors: C. Ferreras1†, B. Pascual-Miguel1†, C. Mestre-Durán1, A. Navarro-Zapata1, L. Clares-Villa1, C. Martín-Cortázar1, R. De Paz2, A. Marcos2, J. L. Vicario3, A. Balas3, F. García-Sánchez3, C. Eguizabal4,5, C. Solano6, M. Mora-Rillo7, B. Soria8,9 and A. Pérez-Martínez1,10,11* Syndrome coronavirus 2 (SARS-CoV-2) pandemic is causing a second outbreak […]
COVID‐19: immunopathology, pathophysiological mechanisms, and treatment options
Authors: Larissa E van Eijk, 1 , † Mathijs Binkhorst, 2 , † Arno R Bourgonje, 3 , ‡ Annette K Offringa, 4 , ‡ Douwe J Mulder, 5 Eelke M Bos, 6 Nikola Kolundzic, 7 , 8 Amaal E Abdulle, 5 Peter HJ van der Voort, 9 Marcel GM Olde Rikkert, 10 Johannes G […]
What is cytokine release syndrome?
Authors: Medical News Today Cytokine release syndrome (CRS) can cause a variety of symptoms, including fever, headaches, and nausea. The symptoms can become severe quickly. CRS occurs when the immune system […]
Cytokine Storm in COVID-19—Immunopathological Mechanisms, Clinical Considerations, and Therapeutic Approaches: The REPROGRAM Consortium Position Paper
Authors: Sonu Bhaskar,1,2,3,* Akansha Sinha,1,4 Maciej Banach,1,5,6,7 Shikha Mittoo,1,8 Robert Weissert,1,9 Joseph S. Kass,1,10 Santhosh Rajagopal,1,11 Anupama R. Pai,1,12 and Shelby Kutty1,13,14 Cytokine storm is an acute hyperinflammatory response that may be responsible for critical illness in many conditions […]
Long-COVID syndrome-associated brain fog and chemofog: Luteolin to the rescue
Authors: Theoharis C Theoharides 1 2 3 4 5, Christos Cholevas 5, Konstantinos Polyzoidis 5, Antonios Politis 6 COVID‐19 leads to severe respiratory problems, but also to long‐COVID syndrome associated primarily with cognitive dysfunction and fatigue. Long‐COVID syndrome symptoms, especially brain […]
COVID-19 ‘brain fog’ inspires search for causes and treatments
Authors: Kelly Servick The true prevalence of cognitive problems in COVID-19 survivors is elusive, and the underlying causes of lingering symptoms are the subject of ongoing studies. But it’s now clear […]
Long Covid and Brain Fog
Authors: Adam Brown BScPT MClScPT FCAMPT Registered Physiotherapist Brain fog can take several different forms and each patient’s description and experience is unique. It involves an alteration in the person’s […]