John Murphy, CEO The COVID-19 Long-haul Foundation Abstract The COVID-19 pandemic has revealed an extensive rheumatologic phenotype extending well beyond the respiratory tract. SARS-CoV-2 infection may be followed by arthralgia, […]
Saliva and SARS-CoV-2 Infection: Molecular, Immunologic, and Clinical Perturbations of the Salivary System in COVID-19
John Murphy, M.D., M.P.H., D.P.H. Abstract Background: Saliva has emerged as a central biological medium in SARS-CoV-2 infection, functioning simultaneously as a diagnostic fluid, a viral reservoir, and a reflection […]
The SARS-CoV-2 Spike Protein: Architecture, Binding Dynamics, and Clearance Evolution Over Five Years
John Murphy, President The COVID Long-haul Foundation Abstract The SARS-CoV-2 spike (S) protein is the principal mediator of viral entry and a key determinant of COVID-19 pathogenesis. This article provides […]
Turmeric as a Possible Treatment for COVID-19-Induced Anosmia and Ageusia
A. Bert Chabot • Margaret P. Huntwork, DOI: 10.7759/cureus.17829 Abstract The coronavirus disease 2019 (COVID-19) pandemic has caused a calamitous perturbation of society worldwide. Anosmia and ageusia (or hyposmia and dysgeusia) have been […]
Otologic and Vestibular Sequelae of SARS-CoV-2 Infection and COVID-19 Vaccination: A Comparative Pathophysiologic Review
John Murphy, The COVID 19 Long-haul Foundation Abstract SARS-CoV-2 has demonstrated a remarkable capacity for multisystem involvement, extending beyond its primary respiratory tropism to affect neurological, vascular, and otologic domains. […]
❄️ COVID-19 and Chilblains: Unraveling the Dermatologic Puzzle in 2025
🔬 Overview As the COVID-19 pandemic enters its fifth year, dermatological manifestations remain a key area of clinical and immunological inquiry. Among these, chilblains—also known as pernio—have emerged as a […]
🩸 COVID-19 and Chronic Venous Insufficiency: 2025 Research Insights on Etiology, Vascular Damage, and Treatment
Chronic Venous Insufficiency (CVI)—a condition where leg veins fail to return blood efficiently to the heart—has gained renewed attention in 2025 due to its association with COVID-19, particularly in patients […]
Incidence of Neurological Manifestations in Critically Ill COVID-19 Patients
Sasa Dragic • Andrea Dolencuk • Danica Momcicevic • et. al., DOI: 10.7759/cureus.85616 Abstract Introduction Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is not primarily a neurotropic virus. However, since angiotensin-converting enzyme 2 (ACE2) receptors are present […]
Ocular Symptoms Among COVID-19 Positive Patients: A Cross-Sectional Survey
Nayef F. Alswaina • Abdulrahman Alsowinea • Yazeed K. Alhabeeb •et. al. DOI: 10.7759/cureus.76671 Abstract Background Coronavirus disease (COVID-19), a widespread viral illness, has been linked to a range of respiratory and other systemic symptoms. Along […]
Is there a role for the adrenal glands in long COVID?
Waldemar Kanczkowski, Felix Beuschlein & Stefan R. Bornstein Nature Reviews Endocrinology volume 18, pages451–452 The symptoms of long COVID and chronic adrenal insufficiency have striking similarities. Therefore, we aim to raise awareness of assessing adrenal function […]