Authors: Amit Gupta, Oshin Sharma, Kandhala Srikanth, Rahul Mishra, Amoli Tandon & Deepak Rajput Indian Journal of Surgery (2022) Published: 11 March 2022 Abstract The new coronavirus (COVID-19) infection, first detected in Wuhan, China in 2019 has become […]
Elevated clotting factor V levels linked to worse outcomes in severe COVID-19 infections
Authors: Jonathan A. Stefely,Bianca B. Christensen,Tasos Gogakos,Jensyn K. Cone Sullivan … See all authors First published: 24 August 2020 https://doi.org/10.1002/ajh.25979 Abstract Coagulopathy causes morbidity and mortality in patients with coronavirus disease 2019 (COVID-19) due […]
Nuts and bolts of COVID-19 associated coagulopathy: the essentials for management and treatment
Authors: Patrick J Lindsay, a Rachel Rosovsky, b Edward A Bittner, c and Marvin G. Chang c ABSTRACT Introduction COVID-19-associated coagulopathy (CAC) is a well-recognized hematologic complication among patients with severe COVID-19 disease, where macro- and micro-thrombosis can […]
Whole genome sequencing reveals host factors underlying critical Covid-19
Authors: Athanasios Kousathanas, Erola Pairo-Castineira, J. Kenneth BaillieArticle Published: 07 March 2022 nature articles article We are providing an unedited version of this manuscript to give early access to its findings. Before final publication, the […]
Pulmonary Vascular Endothelialitis, Thrombosis, and Angiogenesis in Covid-19
Authors.Maximilian Ackermann, M.D., Stijn E. Verleden, Ph.D., Mark Kuehnel, Ph.D., Axel Haverich, M.D., Tobias Welte, M.D., Florian Laenger, M.D., Arno Vanstapel, Ph.D., Christopher Werlein, M.D., Helge Stark, Ph.D., Alexandar Tzankov, M.D., William W. Li, M.D., Vincent W. Li, M.D., et al. July […]
The spike protein of SARS-CoV-2 induces endothelial inflammation through integrin α5β1 and NF-κB signaling
Authors: Juan Pablo Robles 1Magdalena Zamora 1Elva Adan-CastroLourdes Siqueiros-MarquezGonzalo Martinez de la EscaleraCarmen Clapp Open AccessDOI:https://doi.org/10.1016/j.jbc.2022.101695 Vascular endothelial cells (ECs) form a critical interface between blood and tissues that maintains whole-body homeostasis. […]
COVID‐19‐induced endotheliitis: emerging evidence and possible therapeutic strategies
Authors: Eleonora Calabretta, 1 , 12 Jose M. Moraleda, 2 Massimo Iacobelli, 3 Ruben Jara, 4 Israel Vlodavsky, 5 Peter O’Gorman, 6 Antonio Pagliuca, 7 Clifton Mo, 8 Rebecca M. Baron, 9 Alessio Aghemo, 10 , 12 Robert Soiffer, 8 Jawed Fareed, 11 Carmelo Carlo‐Stella, 1 , 12 , * and Paul Richardson 8 , * Br J Haematol. 2021 Apr; 193(1): 43–51.Published online […]
The coagulopathy, endotheliopathy, and vasculitis of COVID-19
Authors: Toshiaki Iba 1, Jean Marie Connors 2, Jerrold H Levy 3 PMID: 32918567 PMCID: PMC7486586 DOI: 10.1007/s00011-020-01401-6 Abstract Background COVID-19-associated coagulopathy (CAC) characterized by the elevated D-dimer without remarkable changes of other global coagulation markers is associated […]
COVID-19-associated coagulopathy: An exploration of mechanisms
Authors: Meaghan E Colling 1, Yogendra Kanthi 2 PMID: 32558620 PMCID: PMC7306998 OI: 10.1177/1358863X20932640 Abstract An ongoing global pandemic of viral pneumonia (coronavirus disease [COVID-19]), due to the virus SARS-CoV-2, has infected millions of people and […]