Authors: Ben Hu, Hua Guo, Peng Zhou & Zheng-Li Shi Nature Reviews Microbiology volume 19, pages141–154 (2021) Abstract Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a highly transmissible and pathogenic coronavirus that emerged in late 2019 […]
Mapping the human genetic architecture of COVID-19
COVID-19 Host Genetics Initiative, Nature (2021) Abstract The genetic makeup of an individual contributes to susceptibility and response to viral infection. While environmental, clinical and social factors play a role in […]
What are Adenovirus-Based Vaccines?
Authors: By Dr. Sanchari Sinha Dutta, Ph.D.Reviewed by Sophia Coveney, B.Sc. Adenoviruses are considered excellent vectors for delivering target antigens to mammalian hosts because of their capability to induce both innate and adaptive immune […]
Insights into How SARS-CoV-2 Causes Brain Pathology
Authors: Anthony L. Komaroff, MD, reviewing Yang AC et al. Nature 2021 Jul Marshall M. Nature 2021 Jul In deceased COVID-19 patients, gene expression in the choroid plexus was altered. People infected with SARS-CoV-2 can […]
Mutational Similarities Between SARS-CoV-2 and Its Predecessors
Authors: | Original story from University of Nebraska–Lincoln, Credit: Pete Linforth/ Pixabay New research from the University of Nebraska-Lincoln has shown that the mutations arising in the COVID-19-causing SARS-CoV-2 virus seem […]
How Precision Medicine, Genomics Research is Decoding COVID-19
Authors: Jessica Kent Studies have sought to discover why the disease affects some individuals more severely than others, how communities can reduce the spread of infection, and which states or […]
SARS-CoV-2 genomics and host cellular susceptibility factors of COVID-19
Authors: FENGYU ZHANG AND MICHAEL D WATERS Coronavirus disease 19 (COVID-19) caused by infection with a novel severe acute respiratory syndrome virus -2 (SARS-CoV-2) has evolved into a pandemic and […]
Primed” for Infection: Cells Damaged by Chronic Lung Disease Can Result in Severe COVID
Authors: TRANSLATIONAL GENOMICS RESEARCH INSTITUTE (TGEN) Results from a TGen-led international study suggest that SARS-CoV-2 takes advantage of genetic changes among patients with pre-existing lung diseases. The results of a study by […]
SARS-CoV-2 viral genomics
Authors: This analysis was performed primarily by Matt Olm (mattolm@stanford.edu) in Justin Sonnenburg’s lab at Stanford University and Alex Crits-Christoph (crits-christoph@berkeley.edu) in Jill Banfield’s lab at University of California, Berkeley […]