Durability of mRNA-1273 vaccine–induced antibodies against SARS-CoV-2 variants

August 29, 2021 | John Murphy | Leave a Comment

Durability of mRNA-1273 vaccine–induced antibodies against SARS-CoV-2 variants

Authors: ViewAmarendra Pegu1,†, Sarah O’Connell1,† View ORCID ProfileStephen D. Schmidt1,†, Sijy O’Dell1,†, View ORCID ProfileChloe A. Talana1, Lilin Lai2, Jim Albert Science 12 Aug 2021: eabj4176m OI: 10.1126/science.abj4176 Abstract SARS-CoV-2 mutations may diminish vaccine-induced protective…[...]

August 29, 2021 | John Murphy | Leave a Comment

Risk of severe COVID-19 disease with ACE inhibitors and angiotensin receptor blockers: cohort study including 8.3 million people

Julia Hippisley-Cox1, Duncan Young2,3, Carol Coupland4, Keith M Channon5, Pui San Tan6, David A Harrison7, Kathryn Rowan8, Paul Aveyard6, Ian D Pavord9, Peter J Watkinson5,10Correspondence to Prof Julia Hippisley-Cox, Primary Care Health Sciences, University of Oxford, Oxford OX1 Abstract…[...]

August 25, 2021 | John Murphy | Leave a Comment

Link between fever, diarrhea, severe COVID-19, and persistent anti-SARS-CoV-2 antibodies

Authors: By Dr. Liji Thomas, MD Jan 7 2021 Ever since the coronavirus disease 2019 (COVID-19) pandemic began, there have been many attempts to understand the nature and duration of immunity…[...]

August 25, 2021 | John Murphy | Leave a Comment

The Epidemiology, Transmission, and Diagnosis of COVID-19

Authors: By: Neesha C. Siriwardane & Rodney Shackelford, DO, Ph.D. April 15, 2020 Introduction to COVID-19 Coronaviruses are enveloped single-stranded RNA viruses of the Coronaviridae family and order Nidovirales (1). The viruses are named for…[...]

August 22, 2021 | John Murphy | Leave a Comment

Study reveals mouth as primary source of COVID-19 infection

While most COVID-19 research has focused on the nose and lungs, this is the first study to identify the mouth as a primary site for coronavirus infection and underscores the…[...]

August 22, 2021 | John Murphy | Leave a Comment

How does coronavirus kill? Clinicians trace a ferocious rampage through the body, from brain to toes

Authors: By Meredith Wadman, Jennifer Couzin-Frankel, Jocelyn Kaiser, Catherine MatacicApr. 17, 2020 , 6:45 PM On rounds in a 20-bed intensive care unit one recent day, physician Joshua Denson assessed two patients with seizures,…[...]

August 18, 2021 | John Murphy | Leave a Comment

Blood molecular markers associated with COVID-19 immunopathology and multi-organ damage

Authors: Yan-Mei ChenYuanting ZhengYing YuYunzhi WangQingxia HuangFeng QianLei SunZhi-Gang SongZiyin ChenJinwen FengYanpeng AnJingcheng YangZhenqiang SuShanyue SunFahui DaiQinsheng ChenQinwei LuPengcheng LiYun LingZhong YangHuiru TangLeming ShiLi JinEdward C HolmesChen DingTong-Yu ZhuYong-Zhen Zhang…[...]

August 18, 2021 | John Murphy | Leave a Comment

Severe COVID-19: what have we learned with the immunopathogenesis?

Authors: Bruno Bordallo, Mozart Bellas, Arthur Fernandes Cortez, Matheus Vieira & Marcelo Pinheiro Advances in Rheumatology volume 60, Article number: 50 (2020) Cite this article Abstract The COVID-19 outbreak caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has become…[...]

August 18, 2021 | John Murphy | Leave a Comment

Pathophysiology of COVID-19:

Mechanisms Underlying Disease Severity and Progression Authors: Mary Kathryn Bohn,1,2, Alexandra Hall,1 Lusia Sepiashvili,1,2, Benjamin Jung,1,2 Shannon, Steele,1 and Khosrow Adeli1,2,3 The global epidemiology of coronavirus disease 2019 (COVID-19) suggests…[...]

August 18, 2021 | John Murphy | Leave a Comment

Potential mechanisms of cerebrovascular diseases in COVID-19 patients

Authors: Manxue Lou 1, Dezhi Yuan 2 3, Shengtao Liao 4, Linyan Tong 1, Jinfang Li 5Affiliations expand Abstract Since the outbreak of coronavirus disease 2019 (COVID-19) in 2019, it is gaining worldwide attention at the moment. Apart from respiratory manifestations,…[...]