Detrimental effects of COVID-19 in the brain and therapeutic options for long COVID: The role of Epstein–Barr virus and the gut–brain axis


Kenji Hashimoto, Molecular Psychiatry (2023) Published: 04 July 2023 Abstract The coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has resulted in a serious public health burden worldwide. In addition to respiratory, heart, and gastrointestinal symptoms, patients infected with SARS-CoV-2 experience a number of persistent neurological and psychiatric symptoms, known as […]

Prevalence of organ impairment in Long COVID patients 6 and 12 months after initial symptoms


Authors:  Pooja Toshniwal PahariaMar 24 2022Reviewed by Danielle Ellis, B.Sc. In a recent study posted to the medRxiv* preprint server, researchers assessed the prevalence of organ impairment in long coronavirus disease 2019 (COVID-19) six months and a year post-COVID-19 at London and Oxford. Multi-organ impairment associated with long COVID-19 is a significant health burden. Standardized multi-organ evaluation […]

Pancreatic damage in COVID‐19: Why? How?


Authors: Ferhat Bacaksız, 1 Berat Ebik, 1 Nazım Ekin, 1 and Jihat Kılıc 2 Int J Clin Pract. 2021 Aug 6 : e14692.doi: 10.1111/ijcp.14692 [Epub ahead of print] PMCID:  PMC8420122PMID: 34331821 Abstract Object We aimed to evaluate the elevation of amylase and lipase enzymes in coronavirus disease 2019 (COVID‐19) patients and their relationship with the severity of COVID‐19. Method In this study, 1378 patients with COVID‐19 infection […]

Consequences of COVID-19 for the Pancreas


Authors: Urszula Abramczyk,1,*Maciej Nowaczyński,2Adam Słomczyński,2Piotr Wojnicz,2Piotr Zatyka,2 and Aleksandra Kuzan1 Int J Mol Sci. 2022 Jan; 23(2): 864.Published online 2022 Jan 13. doi: 10.3390/ijms23020864 Abstract Although coronavirus disease 2019 (COVID-19)-related major health consequences involve the lungs, a growing body of evidence indicates that COVID-19 is not inert to the pancreas either. This review presents a summary of the molecular mechanisms […]

SARS-CoV-2 infects human pancreatic β cells and elicits β cell impairment


aUTHORS: Chien-Ting Wu,1,13Peter V. Lidsky,2,13Yinghong Xiao,2,13Ivan T. Lee,3,4,5,13Ran Cheng,1,6,13Tsuguhisa Nakayama,5,7,13Sizun Jiang,3,13Janos Demeter,1Romina J. Bevacqua,8Charles A. Chang,8,9,10,11Robert L. Whitener,8Anna K. Stalder,12Bokai Zhu,3Han Chen,3 Cell Metab. 2021 Aug 3; 33(8): 1565–1576.e5.Published online 2021 May18. doi: 10.1016/j.cmet.2021.05.013 :  PMC8130512PMID: 34081912 Abstract Emerging evidence points toward an intricate relationship between the pandemic of coronavirus disease 2019 (COVID-19) and diabetes. While preexisting diabetes is […]

Review of COVID-19, part 1: Abdominal manifestations in adults and multisystem inflammatory syndrome in children


Authors: Devaraju Kanmaniraja,a,⁎ Jessica Kurian,a Justin Holder,a Molly Somberg Gunther,a Victoria Chernyak,b Kevin Hsu,a Jimmy Lee,a Andrew Mcclelland,a Shira E. Slasky,a Jenna Le,a and Zina J. Riccia Abstract The coronavirus disease 2019 (COVID -19) pandemic caused by the novel severe acute respiratory syndrome coronavirus (SARS-CoV-2) has affected almost every country in the world, resulting in severe morbidity, mortality and economic hardship, and altering the landscape of […]

COVID-19 also attacks the pancreas; one vaccine dose may be enough for those previously infected


Authors: Nancy Lapid February 3, 2021 COVID-19 attacks the pancreas The new coronavirus directly targets the pancreas, infecting and damaging its insulin producing cells, according to a new study. The findings may help explain why blood sugar problems develop in many COVID-19 patients, and why there have been reports of diabetes developing as a result […]

Long covid: Damage to multiple organs presents in young, low risk patients


Authors: Gareth Iacobucci BMJ 2020; 371 doi: https://doi.org/10.1136/bmj.m4470 (Published 17 November 2020)Cite this as: BMJ 2020;371:m4470 Young, low risk patients with ongoing symptoms of covid-19 had signs of damage to multiple organs four months after initially being infected, a preprint study has suggested.1 Initial data from 201 patients suggest that almost 70% had impairments in one or more organs four months after […]