Host immunological responses facilitate development of SARS-CoV-2 mutations in patients receiving monoclonal antibody treatments

Akshita Gupta,1,2 Angelina Konnova,1,2 Mathias Smet,1,2 Matilda Berkell,1,2 Alessia Savoldi,3 Matteo Morra,3 Vincent Van averbeke,1 Fien H.R. De Winter,1 Denise Peserico,4 Elisa Danese,4 An Hotterbeekx,1 Elda Righi,3 mAb ORCHESTRA working group,5 Pasquale De Nardo,3 Evelina Tacconelli,3 Surbhi Malhotra-Kumar,2 and Samir Kumar-Singh1,2 Journal of Clinical Investigation 10.1172/JCI166032 Abstract…[...]

Read More

No evidence of durable trained immunity after two doses of adenovirus-vectored or mRNA COVID-19 vaccines

Natalie E. Stevens,1,2 Feargal J. Ryan,1,2 Nicole L. Messina,3,4 Stephen J. Blake,1,2 Todd S. Norton,1 Susie Germano,3 Jane James,1 Georgina L. Eden,1 Yee C. Tee,1,2 Miriam A. Lynn,1,2 Rochelle Botten,1 Simone E. Barry,5 Nigel Curtis,3,4 and David J. Lynn1,2 Published July 20, 2023 - September…[...]

Read More

Cutting Edge: Circulating Exosomes with COVID Spike Protein Are Induced by BNT162b2 (Pfizer–BioNTech) Vaccination prior to Development of Antibodies: A Novel Mechanism for Immune Activation by mRNA Vaccines 

Sandhya Bansal; Sudhir Perincheri; Timothy Fleming; Christin Poulson;Brian Tiffany;Ross M. Bremner; Thalachallour Mohanakumar  J Immunol (2021) 207 (10): 2405–2410.https://doi.org/10.4049/jimmunol.2100637 Abstract Severe acute respiratory syndrome corona virus 2 (SARS-CoV-2) causes severe acute respiratory…[...]

Read More

Potential molecular mechanisms of chronic fatigue in long haul COVID and other viral diseases

Carl Gunnar Gottschalk, Daniel Peterson, Jan Armstrong, Konstance Knox & Avik Roy  Infectious Agents and Cancer volume 18, Article number: 7 (2023) Cite this article, A Correction to this article was published on 24 April 2023 Abstract Historically, COVID-19 emerges as one of…[...]

Read More