John Murphy, CEO The COVID-19 Long haul Foundation Abstract Post–acute sequelae of SARS-CoV-2 infection (PASC), widely referred to as Long COVID, has emerged as a complex, heterogeneous, and often debilitating […]
Post-Vaccination Spike Protein Migration: Genomic Mechanisms of Motility, Pathological Spread, and Long-Term Implications
Author: John Murphy, M.D. CEO Covid-19 Long-haul Foundation Abstract Messenger RNA (mRNA) vaccines have revolutionized infectious disease prevention, offering rapid deployment and robust immunogenicity. However, emerging evidence suggests that the […]
Spatial transcriptomics unveils the in situ cellular and molecular hallmarks of the lung in fatal COVID-19
Carlos Garcia-Prieto, Eva Musulen, Veronica Davalos, et. al.doi: https://doi.org/10.1101/2024.07.03.601404 00010010 Abstract Severe Coronavirus disease 2019 (COVID-19) induces heterogeneous and progressive diffuse alveolar damage (DAD) highly disrupting lung tissue architecture and homeostasis, hampering disease management and leading to […]
Pathological sequelae of long-haul COVID
Saurabh Mehandru & Miriam Merad, Nature Immunology volume 23, pages194–202 ( Abstract The world continues to contend with successive waves of coronavirus disease 2019 (COVID-19), fueled by the emergence of viral variants. At the same time, […]
Improvement of immune dysregulation in individuals with long COVID at 24-months following SARS-CoV-2 infection
Chansavath Phetsouphanh, Brendan Jacka, et. al., Nature Communications volume 15, Article number: 3315 (2024) Abstract This study investigates the humoral and cellular immune responses and health-related quality of life measures in individuals with mild to moderate long […]