Category: Pathophysiology

Pathological sequelae of long-haul COVID

Posted on | Posted on John Murphy | Leave a Comment on Pathological sequelae of long-haul COVID

Saurabh Mehandru & Miriam Merad, Nature Immunology volume 23, pages194–202 ( Abstract The world continues to contend with successive waves of coronavirus disease 2019 (COVID-19), fueled by the emergence of viral variants. At the same time, persistent, prolonged and often debilitating sequelae are increasingly recognized in convalescent individuals, named ‘post-COVID-19 syndrome’ or ‘long-haul COVID’. Clinical symptomatology includes fatigue, malaise, dyspnea, defects […]

Improvement of immune dysregulation in individuals with long COVID at 24-months following SARS-CoV-2 infection

Posted on | Posted on John Murphy | Leave a Comment on Improvement of immune dysregulation in individuals with long COVID at 24-months following SARS-CoV-2 infection

Chansavath Phetsouphanh, Brendan Jacka, et. al., Nature Communications volume 15, Article number: 3315 (2024) Abstract This study investigates the humoral and cellular immune responses and health-related quality of life measures in individuals with mild to moderate long COVID (LC) compared to age and gender matched recovered COVID-19 controls (MC) over 24 months. LC participants show elevated nucleocapsid IgG levels at 3 months, […]