Spatial transcriptomics unveils the in situ cellular and molecular hallmarks of the lung in fatal COVID-19

October 14, 2024 | John Murphy | Leave a Comment

Carlos Garcia-Prieto, Eva Musulen, Veronica Davalos, et. al.doi: https://doi.org/10.1101/2024.07.03.601404 00010010 Abstract Severe Coronavirus disease 2019 (COVID-19) induces heterogeneous and progressive diffuse alveolar damage (DAD) highly disrupting lung tissue architecture and homeostasis, hampering disease management and leading to…[...]

Pathological sequelae of long-haul COVID

September 12, 2024 | John Murphy | Leave a Comment

Saurabh Mehandru & Miriam Merad, Nature Immunology volume 23, pages194–202 ( Abstract The world continues to contend with successive waves of coronavirus disease 2019 (COVID-19), fueled by the emergence of viral variants. At the same time,…[...]

Improvement of immune dysregulation in individuals with long COVID at 24-months following SARS-CoV-2 infection

August 11, 2024 | John Murphy | Leave a Comment

Chansavath Phetsouphanh, Brendan Jacka, et. al., Nature Communications volume 15, Article number: 3315 (2024) Abstract This study investigates the humoral and cellular immune responses and health-related quality of life measures in individuals with mild to moderate long…[...]