In the Eye of the Storm: How Covid-19 Impacts the Eye


Authors: William A. Haseltine Forbes November 13, 2022 While Covid-19 is commonly associated with infection of the lungs, heart and other vital organs, a growing body of evidence suggests that infection can also impact the eye. Approximately 1 in 10 people exposed to Covid-19 experience at least one eye problem, such as dryness, redness, blurred […]

Adverse effects of COVID-19 mRNA vaccines: the spike hypothesis


Published:April 20, 2022DOI:https://doi.org/10.1016/j.molmed.2022.04.0 Authors: oannis P. Trougakos Evangelos Terpos Harry Alexopoulos Efstathios Kastritis Evangelos Andreakos Meletios A. Dimopoulos Highlights Coronavirus disease 2019 (COVID-19) mRNA vaccines induce robust immune responses against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), yet their cellular/molecular mode of action and the etiology of the induced adverse events (AEs) remain elusive. Lipid […]

Less Than 1 In 100 Million Chance That COVID-19 Has Natural Origin


Authors: Hans Mahncke via The Epoch Times October 24, 2022 A new study on the origins of the pandemic, “Endonuclease fingerprint indicates a synthetic origin of SARS-CoV2,” published on the preprint server bioRxiv, concludes that it is highly likely that the SARS-CoV-2 virus that causes COVID-19 originated in a laboratory. The odds of a natural origin, according to the […]

Coronavirus and blood clots: Causes, effects and treatment


Authors: Nascimento Pinto MSN The effects of Covid-19 on people are varied but city doctors have observed that there is a possibility of heart attacks, especially in youngsters.  Some city experts say heart attacks after Covid-19 are caused due to the presence of blood clots in the body. However, others believe there is neither any scientific evidence to […]

Understanding COVID-19 through genome-wide association studies


Authors: Tom H. Karlsen  Nature Genetics volume 54, pages368–369 (2022)Cite this article 8742 Accesses 1 Citations 87 Altmetric Defining the most appropriate phenotypes in genome-wide association studies of COVID-19 is challenging, and two new publications demonstrate how case-control definitions critically determine outcomes and downstream clinical utility of findings. Exploring self-reported data from more than 700,000 participants in a direct-to-consumer ancestry genetics […]

SARS-CoV-2 Infection and the Liver


Authors: Katie Morgan,1,*Kay Samuel,2Martin Vandeputte,1Peter C. Hayes,1 and John N. Plevris1 Pathogens. 2020 Jun; 9(6): 430.Published online 2020 May 30. doi: 10.3390/pathogens9060430 PMCID: PMC7350360PMID: 32486188 Abstract A novel strain of coronoviridae (SARS-CoV-2) was reported in Wuhan China in December 2019. Initially, infection presented with a broad spectrum of symptoms which typically included muscle aches, fever, dry cough, and shortness of breath. SARS-CoV-2 […]

Intestinal Damage in COVID-19: SARS-CoV-2 Infection and Intestinal Thrombosis


Authors: Xiaoming Wu1, Haijiao Jing1, Chengyue Wang1, Yufeng Wang1, Nan Zuo1, Tao Jiang2*, Valerie A. Novakovic3 and Jialan Shi1,3,4* Front. Microbiol., 22 March 2022 | https://doi.org/10.3389/fmicb.2022.860931 The intestinal tract, with high expression of angiotensin-converting enzyme 2 (ACE2), is a major site of extrapulmonary infection in COVID-19. During pulmonary infection, the virus enters the bloodstream forming viremia, which infects and damages extrapulmonary organs. Uncontrolled viral […]

The ongoing enigma of SARS‐CoV‐2 and platelet interaction


Authors: Younes Zaid, PhD 1 , 2 and Fadila Guessous, PhD 3 , 4 Res Pract Thromb Haemost. 2022 Jan; 6(1): e12642.Published online 2022 Jan 25. doi: 10.1002/rth2.12642 PMCID:  PMC8787413PMID :  35106430 Abstract Since the onset of the global pandemic of coronavirus disease 2019 (COVID‐19), there is an urgent need to understand the pathogenesis of the common inflammatory and thrombotic complications associated with this […]

Consequences of COVID-19 for the Pancreas


Authors: Urszula Abramczyk,1,*Maciej Nowaczyński,2Adam Słomczyński,2Piotr Wojnicz,2Piotr Zatyka,2 and Aleksandra Kuzan1 Int J Mol Sci. 2022 Jan; 23(2): 864.Published online 2022 Jan 13. doi: 10.3390/ijms23020864 Abstract Although coronavirus disease 2019 (COVID-19)-related major health consequences involve the lungs, a growing body of evidence indicates that COVID-19 is not inert to the pancreas either. This review presents a summary of the molecular mechanisms […]

ACE2-independent infection of T lymphocytes by SARS-CoV-2


Authors: Xu-Rui Shen, Rong Geng, Qian Li,  Ying Chen, Shu-Fen Li, Qi Wang, Juan Min, Yong Yang, Bei Li, Yong Yang, Bei Li, Ren-Di Jiang, Xi Wang, Xiao-Shuang Zheng, Yan Zhu, Jing-Kun Jia, Xing-Lou Yang, Mei-Qin Liu, Qian-Chun Gong, Yu-Lan Zhang, Zhen-Qiong Guan, Hui-Ling Li, Zhen-Hua Zheng, Zheng-Li Shi, Hui-Lan Zhang, Ke Peng & Peng Zhou  Signal Transduction and Targeted Therapy volume 7, Article number: 83 (2022)  Abstract SARS-CoV-2 induced marked lymphopenia in severe patients with COVID-19. However, whether lymphocytes are targets of viral infection is […]